Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 2/20 | 0.42 |
| ▸ | MMP2 | P08253 | 2/20 | 0.42 |
| ▸ | MMP9 | P14780 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | NDUFS8 | O00217 | 1/20 | 0.41 |
| ▸ | COXFA4 | O00483 | 1/20 | 0.41 |
| ▸ | NDUFAB1 | O14561 | 1/20 | 0.41 |
| ▸ | NDUFA1 | O15239 | 1/20 | 0.41 |
| ▸ | NDUFS4 | O43181 | 1/20 | 0.41 |
| ▸ | NDUFB5 | O43674 | 1/20 | 0.41 |
| ▸ | NDUFB3 | O43676 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4754381 | 1.00 | KMT2A (0.47) | KMT2AMEN1LMNAALDH1A1POLB | |
| SCHEMBL4017825 | 0.92 | MMP1 (0.50) | KMT2AMEN1LMNAALDH1A1POLB | |
| SCHEMBL4015557 | 0.90 | POLB (0.49) | KMT2AMEN1LMNAALDH1A1POLB | |
| SCHEMBL4015555 | 0.90 | POLB (0.49) | KMT2AMEN1LMNAALDH1A1POLB | |
| SCHEMBL4017819 | 0.88 | MEN1 (0.47) | KMT2AMEN1LMNAALDH1A1POLB | |
| SCHEMBL4017820 | 0.87 | MAPT (0.50) | KMT2AMEN1LMNAALDH1A1POLB | |
| SCHEMBL4017823 | 0.87 | MAPT (0.50) | KMT2AMEN1LMNAALDH1A1POLB | |
| SCHEMBL4014345 | 0.87 | MMP1 (0.48) | KMT2AMEN1MMP1MMP2MMP9 | |
| SCHEMBL4670737 | 0.86 | HDAC4 (0.46) | KMT2AMEN1LMNAALDH1A1POLB | |
| SCHEMBL4016316 | 0.86 | MEN1 (0.43) | KMT2AMEN1LMNAALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008152097-A1 | CINNAMIC ACID DERIVATIVES AS MODULATORS OF THE EP2 RECEPTOR | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2008-12-18 | — | — | WO | claimed |
| EP-2003118-A1 | Cinnamic acid derivatives as modulators of EP2 receptors | Bayer Schering Pharma Aktiengesellschaft (DE) | 2008-12-17 | — | — | EP | claimed |
| WO-2008152097-A1 | CINNAMIC ACID DERIVATIVES AS MODULATORS OF THE EP2 RECEPTOR | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2008-12-18 | — | — | WO | disclosed |
| WO-2008152097-A1 | CINNAMIC ACID DERIVATIVES AS MODULATORS OF THE EP2 RECEPTOR | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2008-12-18 | — | — | WO | disclosed |
| EP-2003118-A1 | Cinnamic acid derivatives as modulators of EP2 receptors | Bayer Schering Pharma Aktiengesellschaft (DE) | 2008-12-17 | — | — | EP | disclosed |
| EP-2003118-A1 | Cinnamic acid derivatives as modulators of EP2 receptors | Bayer Schering Pharma Aktiengesellschaft (DE) | 2008-12-17 | — | — | EP | disclosed |