Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.38 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4669514 | 1.00 | MEN1 (0.46) | MEN1KMT2AMAPTCYP1A2POLB | |
| SCHEMBL4752215 | 0.90 | MEN1 (0.43) | MEN1KMT2AMAPTCYP1A2POLB | |
| SCHEMBL4668502 | 0.90 | MEN1 (0.43) | MEN1KMT2AMAPTCYP1A2POLB | |
| SCHEMBL4015557 | 0.90 | POLB (0.49) | MEN1KMT2AMAPTCYP1A2POLB | |
| SCHEMBL4668484 | 0.90 | MEN1 (0.44) | MEN1KMT2AMAPTCYP1A2POLB | |
| SCHEMBL4015555 | 0.90 | POLB (0.49) | MEN1KMT2AMAPTCYP1A2POLB | |
| SCHEMBL4017819 | 0.89 | MEN1 (0.47) | MEN1KMT2AMAPTPOLBHDAC3 | |
| SCHEMBL4014345 | 0.88 | MMP1 (0.48) | MEN1KMT2A | |
| SCHEMBL4017820 | 0.88 | MAPT (0.50) | MEN1KMT2AMAPTCYP1A2POLB | |
| SCHEMBL4017823 | 0.88 | MAPT (0.50) | MEN1KMT2AMAPTCYP1A2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008152097-A1 | CINNAMIC ACID DERIVATIVES AS MODULATORS OF THE EP2 RECEPTOR | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2008-12-18 | — | — | WO | claimed |
| WO-2008152097-A1 | CINNAMIC ACID DERIVATIVES AS MODULATORS OF THE EP2 RECEPTOR | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2008-12-18 | — | — | WO | disclosed |