SCHEMBL4013658

SCHEMBL4013658

COc1cc(F)ccc1Oc1ncccc1C1=CCN(C(=O)O)CC1

nearest known ligand 0.47

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CCNT1 O60563 20/20 0.47
CDK9 P50750 20/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4009606 0.90 MAPT (0.45) CCNT1CDK9
SCHEMBL4011858 0.90 PDE10A (0.44) CCNT1CDK9
SCHEMBL4015332 0.90 PDE10A (0.51) CCNT1CDK9
SCHEMBL4013497 0.90 CCNT1 (0.44) CCNT1CDK9
SCHEMBL4009648 0.86 CCNT1 (0.46) CCNT1CDK9
SCHEMBL4007261 0.86 PDE10A (0.46) CCNT1CDK9
SCHEMBL4009241 0.84 PDE10A (0.44) CCNT1CDK9
SCHEMBL16992066 0.83 PDE10A (0.46) CCNT1CDK9
SCHEMBL4010834 0.82 PDE10A (0.47) CCNT1CDK9
SCHEMBL4007141 0.82 PDE10A (0.42) CCNT1CDK9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009081259-A1 PHENOXY-PYRIDYL DERIVATIVES PFIZER INC. (US) 2009-07-02 WO disclosed