Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 2/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | HRH2 | P25021 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | TRPC6 | Q9Y210 | 1/20 | 0.31 |
| ▸ | TACR1 | P25103 | 2/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.31 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2429711 | 0.88 | TACR1 (0.33) | TACR1SLC6A4KCNH2S1PR2 | |
| SCHEMBL2426754 | 0.87 | TACR1 (0.39) | POLBTACR1RORC | |
| SCHEMBL3924879 | 0.86 | CTSK (0.37) | OPRD1OPRK1HRH2HRH1CTSK | |
| SCHEMBL2424078 | 0.85 | TACR1 (0.42) | TACR1SLC6A4KCNH2 | |
| SCHEMBL2428531 | 0.79 | MAPK1 (0.35) | OPRD1TACR1SLC6A4KCNH2MAPK1 | |
| SCHEMBL2425751 | 0.79 | CNR2 (0.37) | POLBSMN1; SMN2TACR1 | |
| SCHEMBL2428029 | 0.76 | TACR1 (0.37) | TACR1SLC6A4KCNH2MAPK1 | |
| SCHEMBL12290476 | 0.75 | CCR5 (0.39) | POLBTACR1LMNAMAPT | |
| SCHEMBL2429202 | 0.75 | TACR1 (0.42) | TACR1SLC6A4KCNH2 | |
| SCHEMBL2429704 | 0.73 | ACACB (0.39) | TACR1SLC6A4KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009009411-A1 | SUBSTITUTED HETEROCYCLIC ETHERS AND THEIR USE IN CNS DISORDERS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2009-01-15 | — | — | WO | disclosed |