⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3948809 | 0.92 | LMNA (0.32) | — | |
| SCHEMBL13906749 | 0.92 | LMNA (0.32) | — | |
| SCHEMBL4020116 | 0.92 | LMNA (0.32) | — | |
| SCHEMBL13905109 | 0.87 | LMNA (0.30) | — | |
| SCHEMBL3957319 | 0.87 | LMNA (0.30) | — | |
| SCHEMBL3374939 | 0.85 | XDH (0.32) | — | |
| SCHEMBL3286137 | 0.85 | XDH (0.32) | — | |
| SCHEMBL3953317 | 0.84 | CCNT1 (0.30) | — | |
| SCHEMBL13906779 | 0.84 | CCNT1 (0.30) | — | |
| SCHEMBL3952292 | 0.83 | ADORA2A (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090253648-A1 | Tricyclic-Nucleoside Compounds for Treating Viral Infections | SMITHKLINE BEECHAM CORPORATION (US) | 2009-10-08 | — | — | US | disclosed |
| US-7524825-B2 | Tricyclic-nucleoside compounds for treating viral infections | SMITHKLINE BEECHAM CORPORATION (US) | 2009-04-28 | — | — | US | disclosed |
| US-20090048189-A1 | TRICYCLIC-NUCLEOSIDE COMPOUNDS FOR TREATING VIRAL INFECTIONS | GENELABS TECHNOLOGIES, INC. | 2009-02-19 | — | — | US | disclosed |
| US-20060252715-A1 | Tricyclic-nucleoside compounds for treating viral infections | GENELABS TECHNOLOGIES, INC. | 2006-11-09 | — | — | US | disclosed |