Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 4/20 | 0.77 |
| ▸ | NQO1 | P15559 | 1/20 | 0.68 |
| ▸ | RELA | Q04206 | 1/20 | 0.61 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 3/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.50 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.50 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.50 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.50 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenetole SCHEMBL10779391 | 0.97 | LTA4H (0.81) | LTA4HNQO1RELAKCNA3TSHR | |
| Phenetole SCHEMBL18492 | 0.97 | — | — | |
| Phenetole SCHEMBL499918 | 0.97 | LTA4H (0.81) | LTA4HNQO1RELAKCNA3TSHR | |
| Phenetole SCHEMBL28966428 | 0.94 | LTA4H (0.77) | LTA4HNQO1RELAKCNA3TSHR | |
| Phenetole SCHEMBL14954246 | 0.94 | LTA4H (0.77) | LTA4HNQO1RELAKCNA3TSHR | |
| Phenetole SCHEMBL28696840 | 0.94 | LTA4H (0.77) | LTA4HNQO1RELAKCNA3TSHR | |
| Phenetole SCHEMBL28966473 | 0.94 | LTA4H (0.77) | LTA4HNQO1RELAKCNA3TSHR | |
| Phenetole SCHEMBL3991967 | 0.94 | LTA4H (0.77) | LTA4HNQO1RELAKCNA3TSHR | |
| Phenetole SCHEMBL28364557 | 0.94 | LTA4H (0.77) | LTA4HNQO1RELAKCNA3TSHR | |
| Phenetole SCHEMBL11569608 | 0.94 | LTA4H (0.77) | LTA4HNQO1RELAKCNA3TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1826121-B | Application of phenyl and pyridyl derivatives in preparation of drugs for regulating calcium ion release and activating calcium ion channels | SYNTA PHARMACEUTICALS CORP | 2013-05-29 | — | — | CN | disclosed |
| CN-101947218-A | The method of modulating calcium ion-release-activated calcium ion channels | SYNTA PHARMACEUTICALS CORP | 2011-01-19 | — | — | CN | disclosed |
| CN-101842087-A | Improved tablet coating | SANOFI AVENTIS HEALTHCARE PTY | 2010-09-22 | — | — | CN | disclosed |
| EP-2074103-A1 | 6-PHENYLPYRIMIDINONES AS PIM MODULATORS | Exelixis, Inc. (US) | 2009-07-01 | — | — | EP | disclosed |
| WO-2008133955-A1 | 6-PHENYLPYRIMIDINONES AS PIM MODULATORS | EXELIXIS, INC. (US) | 2008-11-06 | — | — | WO | disclosed |
| CN-101137624-A | Compounds for inflammation and immune-related uses | SYNTA PHARMACEUTICALS CORP (US) | 2008-03-05 | — | — | CN | disclosed |
| CN-1826121-A | Method for regulating and controlling calcium ion release to activate calcium ion channel | SYNTA PHARMACEUTICALS CORP (US) | 2006-08-30 | — | — | CN | disclosed |
| CN-1826120-A | Compounds for inflammation and immune-related uses | SYNTA PHARMACEUTICALS CORP (US) | 2006-08-30 | — | — | CN | disclosed |
| EP-0846679-B1 | Process for preparing 1,3-disubstituted urea | SUMIKA FINE CHEMICALS CO LTD (JP) | 2000-09-06 | — | — | EP | disclosed |
| US-5902899-A | Process for preparing 1, 3-disubstituted urea | SUMIKA FINE CHEMICALS CO., LTD. (JP) | 1999-05-11 | — | — | US | disclosed |
| EP-0846679-A2 | Process for preparing 1,3-disubstituted urea | SUMIKA FINE CHEMICALS Co., Ltd. (JP) | 1998-06-10 | — | — | EP | disclosed |
| US-5256242-A | Mixing ferrite powders of different molar percentages, forming, sintering and hot isostatic pressing | NGK INSULATORS, LTD. (JP) | 1993-10-26 | — | — | US | disclosed |