Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM1 | Q13255 | 10/20 | 0.56 |
| ▸ | GRM5 | P41594 | 10/20 | 0.56 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.54 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.52 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.42 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.42 |
| ▸ | CDK9 | P50750 | 1/20 | 0.42 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
| ▸ | BTK | Q06187 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4003764 | 0.94 | GRM1 (0.58) | GRM1GRM5PDE10APDK4SCN9A | |
| SCHEMBL13769472 | 0.90 | GRM1 (0.54) | GRM1GRM5PDE10APDK4SCN9A | |
| SCHEMBL4305255 | 0.90 | GRM1 (0.53) | GRM1GRM5PDE10APDK4SCN9A | |
| SCHEMBL4010237 | 0.88 | PDE10A (0.44) | GRM1GRM5PDE10ACCNT1CDK9 | |
| SCHEMBL4013686 | 0.87 | GRM1 (0.58) | GRM1GRM5PDE10APDK4SCN9A | |
| SCHEMBL4011635 | 0.85 | PDE10A (0.55) | GRM1GRM5PDE10APDK4CCNT1 | |
| SCHEMBL4013818 | 0.83 | PDE10A (0.55) | GRM1GRM5PDE10APDK4CCNT1 | |
| SCHEMBL13769766 | 0.83 | PDE10A (0.55) | GRM1GRM5PDE10APDK4CCNT1 | |
| SCHEMBL13769826 | 0.82 | PDE10A (0.69) | GRM1GRM5PDE10APDK4TNK2 | |
| SCHEMBL4014879 | 0.82 | PDE10A (0.58) | GRM1GRM5PDE10APDK4HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009081259-A1 | PHENOXY-PYRIDYL DERIVATIVES | PFIZER INC. (US) | 2009-07-02 | — | — | WO | disclosed |