SCHEMBL4015064

SCHEMBL4015064

Clc1ccc(Oc2ccc(Cl)cc2Oc2cc(Cl)ccc2Oc2ccc(Cl)cc2Cl)c(Cl)c1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TTR P02766 7/20 0.67
SLC6A2 P23975 3/20 0.67
SLC6A3 Q01959 3/20 0.67
HPGD P15428 2/20 0.67
NR1I2 O75469 1/20 0.67
LMNA P02545 1/20 0.67
PGR P06401 1/20 0.67
HSP90AA1 P07900 1/20 0.67
ADORA3 P0DMS8 1/20 0.67
MAPT P10636 1/20 0.67
HSPA5 P11021 1/20 0.67
CBR1 P16152 1/20 0.67
TBXA2R P21731 1/20 0.67
AGTR1 P30556 1/20 0.67
SLC6A4 P31645 2/20 0.50
RHEB Q15382 1/20 0.50
ALDH1A1 P00352 1/20 0.49
POLB P06746 1/20 0.49
GAA P10253 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7186092 0.93 TTR (0.75) TTRSLC6A2SLC6A3HPGDNR1I2
SCHEMBL7799904 0.89 TTR (0.60) TTRSLC6A2SLC6A3HPGDNR1I2
SCHEMBL30518850 0.88 TTR (0.64) TTRSLC6A2SLC6A3HPGDNR1I2
SCHEMBL20242172 0.88 TTR (0.64) TTRSLC6A2SLC6A3HPGDNR1I2
SCHEMBL676629 0.87 TTR (0.73) TTRSLC6A2SLC6A3HPGDNR1I2
SCHEMBL13167632 0.87 CYP1A2 (0.59) TTRSLC6A2SLC6A3HPGDNR1I2
SCHEMBL11402177 0.86 TTR (0.62) TTRSLC6A2SLC6A3HPGDNR1I2
SCHEMBL4135441 0.83 TTR (0.75) TTRSLC6A2SLC6A3HPGDNR1I2
SCHEMBL4965689 0.83 TTR (0.58) TTRSLC6A2SLC6A3HPGDNR1I2
SCHEMBL7030457 0.82 TTR (0.53) TTRSLC6A2SLC6A3HPGDNR1I2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7544722-B2 aquatic environment; block polymers having a carbon and/or silicone backbone with a pendant biocidal/fouling release group; dimethylsiloxane-vinylmethyl siloxane-Triclosan methacrylate ester block polymer; isoprene-triclosan methacrylate-methacrylic acid with pendant polydimethylsiloxane at the carboxy NDSU RESEARCH FOUNDATION (US) 2009-06-09 US disclosed
EP-1663531-A4 ANTI-FOULING MATERIALS NDSU RES FOUNDATION (US) 2007-11-28 EP disclosed
US-20070021529-A1 POLYMERIC MATERIALS WITH ANTI-FOULING ACTIVITY NDSU RESEARCH FOUNDATION 2007-01-25 US disclosed
EP-1663531-A2 ANTI-FOULING MATERIALS NDSU Research Foundation (US) 2006-06-07 EP disclosed
WO-2005030405-A2 ANTI-FOULING MATERIALS NDSU RESEARCH FOUNDATION (US) 2005-04-07 WO disclosed