Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 7/20 | 0.73 |
| ▸ | SLC6A2 | P23975 | 9/20 | 0.58 |
| ▸ | SLC6A3 | Q01959 | 7/20 | 0.58 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | PGR | P06401 | 1/20 | 0.58 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.58 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | CBR1 | P16152 | 1/20 | 0.58 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.58 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.58 |
| ▸ | SLC6A4 | P31645 | 9/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12850975 | 0.91 | TTR (0.67) | TTRSLC6A2SLC6A3NR1I2LMNA | |
| SCHEMBL4015064 | 0.87 | TTR (0.67) | TTRSLC6A2SLC6A3NR1I2LMNA | |
| SCHEMBL196490 | 0.85 | TTR (0.62) | TTRSLC6A2SLC6A3NR1I2LMNA | |
| SCHEMBL29687129 | 0.85 | TTR (0.62) | TTRSLC6A2SLC6A3NR1I2LMNA | |
| SCHEMBL13236279 | 0.85 | TTR (1.00) | TTRSLC6A2SLC6A3NR1I2LMNA | |
| SCHEMBL7186092 | 0.85 | TTR (0.75) | TTRSLC6A2SLC6A3NR1I2LMNA | |
| SCHEMBL3365226 | 0.84 | SLC6A4 (0.64) | TTRSLC6A2SLC6A3NR1I2LMNA | |
| SCHEMBL13264608 | 0.84 | TTR (0.76) | TTRSLC6A2SLC6A3NR1I2LMNA | |
| Ammonia Solution, Strong SCHEMBL4261558 | 0.83 | TTR (0.61) | TTRSLC6A2SLC6A3NR1I2LMNA | |
| SCHEMBL2127233 | 0.83 | TRPV4 (0.55) | TTRSLC6A2SLC6A3LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6133483-A | Process for the production of 2,4,4'-trichloro-2'-methoxydiphenyl ether | CLEARY THOMAS F (US) | 2000-10-17 | — | — | US | claimed |
| US-8541556-B1 | Lignin derivatives and uses thereof | EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) | 2013-09-24 | — | — | US | disclosed |
| US-20130231295-A1 | LIGNIN DERIVATIVES AND USES THEREOF | EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) | 2013-09-05 | — | — | US | disclosed |
| US-8278400-B2 | Antifouling materials containing cationic polysiloxanes | NDSU RESEARCH FOUNDATION (US) | 2012-10-02 | — | — | US | disclosed |
| US-8278400-B2 | Antifouling materials containing cationic polysiloxanes | NDSU RESEARCH FOUNDATION (US) | 2012-10-02 | — | — | US | disclosed |
| US-8053535-B2 | Polysiloxanes with anti-fouling activity | NDSU RESEARCH FOUNDATION (US) | 2011-11-08 | — | — | US | disclosed |
| US-20100204399-A1 | ANTIFOULING MATERIALS CONTAINING CATIONIC POLYSILOXANES | NDSU RESEARCH FOUNDATION | 2010-08-12 | — | — | US | disclosed |
| US-20100204399-A1 | ANTIFOULING MATERIALS CONTAINING CATIONIC POLYSILOXANES | NDSU RESEARCH FOUNDATION | 2010-08-12 | — | — | US | disclosed |
| US-7771833-B2 | Anti-fouling materials containing cationic polysiloxanes | NDSU RESEARCH FOUNDATION (US) | 2010-08-10 | — | — | US | disclosed |
| US-7771833-B2 | Anti-fouling materials containing cationic polysiloxanes | NDSU RESEARCH FOUNDATION (US) | 2010-08-10 | — | — | US | disclosed |
| US-20090018276-A1 | Polysiloxanes with anti-fouling activity | NDSU RESEARCH FOUNDATION | 2009-01-15 | — | — | US | disclosed |
| US-20090018276-A1 | Polysiloxanes with anti-fouling activity | NDSU RESEARCH FOUNDATION | 2009-01-15 | — | — | US | disclosed |
| US-20070042199-A1 | Anti-fouling materials containing cationic polysiloxanes | NDSU RESEARCH FOUNDATION | 2007-02-22 | — | — | US | disclosed |
| US-20070042199-A1 | Anti-fouling materials containing cationic polysiloxanes | NDSU RESEARCH FOUNDATION | 2007-02-22 | — | — | US | disclosed |
| US-7163923-B2 | Bactericides, fungicides, viricides | CELMED ONCOLOGY (USA), INC. (CA) | 2007-01-16 | — | — | US | disclosed |
| US-6133483-A | Process for the production of 2,4,4'-trichloro-2'-methoxydiphenyl ether | CLEARY THOMAS F (US) | 2000-10-17 | — | — | US | disclosed |
| US-6133483-A | Process for the production of 2,4,4'-trichloro-2'-methoxydiphenyl ether | CLEARY THOMAS F (US) | 2000-10-17 | — | — | US | disclosed |
| US-6133483-A | Process for the production of 2,4,4'-trichloro-2'-methoxydiphenyl ether | CLEARY THOMAS F (US) | 2000-10-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130231295-A1 | LIGNIN DERIVATIVES AND USES THEREOF | DCXR, LCT, LSS | TTR 4141/4885SLC6A2 4500/4885SLC6A3 4582/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.