SCHEMBL4135441

SCHEMBL4135441

Oc1ccc(Cl)cc1Oc1ccc(Cl)cc1Cl

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TTR P02766 7/20 0.75
HPGD P15428 2/20 0.75
NR1I2 O75469 1/20 0.75
LMNA P02545 1/20 0.75
PGR P06401 1/20 0.75
HSP90AA1 P07900 1/20 0.75
ADORA3 P0DMS8 1/20 0.75
MAPT P10636 1/20 0.75
HSPA5 P11021 1/20 0.75
CBR1 P16152 1/20 0.75
TBXA2R P21731 1/20 0.75
SLC6A2 P23975 1/20 0.75
AGTR1 P30556 1/20 0.75
SLC6A3 Q01959 1/20 0.75
TSHR P16473 1/20 0.56
HSD17B10 Q99714 1/20 0.56
ALDH1A1 P00352 1/20 0.47
POLB P06746 1/20 0.47
GAA P10253 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11882989 0.88 TTR (0.81) TTRHPGDNR1I2LMNAPGR
Triclosan SCHEMBL526378 0.86 TTR (1.00) TTRHPGDNR1I2LMNAPGR
Triclosan SCHEMBL29354475 0.86 TTR (1.00) TTRHPGDNR1I2LMNAPGR
Triclosan SCHEMBL29367506 0.86 TTR (1.00) TTRHPGDNR1I2LMNAPGR
SCHEMBL8659315 0.86 TTR (0.55) TTRHPGDNR1I2LMNAPGR
Triclosan SCHEMBL29356111 0.86 TTR (1.00) TTRHPGDNR1I2LMNAPGR
Triclosan SCHEMBL3269 0.86 TTR (1.00) TTRHPGDNR1I2LMNAPGR
SCHEMBL7186092 0.85 TTR (0.75) TTRHPGDNR1I2LMNAPGR
SCHEMBL240470 0.85 TTR (0.76) TTRHPGDNR1I2LMNAPGR
Triclosan SCHEMBL8015104 0.84 TTR (0.96) TTRHPGDNR1I2LMNAPGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 105 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2591772-B1 New coated controlled release active agent carriers OMYA INT AG (CH) 2016-05-04 EP claimed
EP-2747752-B1 NEW COATED CONTROLLED RELEASE ACTIVE AGENT CARRIERS OMYA INT AG (CH) 2015-10-07 EP claimed
US-8894622-B2 Bottle for packaging liquid that is to be dispensed drop by drop, with antibacterial protection LABORATOIRES THEA (FR) 2014-11-25 US claimed
EP-2642971-A2 A SHAVING COMPOSITION FOR PSEUDOFOLLICULITIS BARBAE TREATMENT NRN Finance APS (DK) 2013-10-02 EP claimed
WO-2012069061-A2 A SHAVING COMPOSITION FOR PSEUDOFOLLICULITIS BARBAE TREATMENT NRN FINANCE APS (DK) 2012-05-31 WO claimed
US-7632348-B2 cement; expanded polymeric particles with specific particle size, bulk density and aspect ratio, containing antimicorbial agents such as Triclosan, zinc carboxylate; boric acids; sodium dichromate etc. used to make concrete masonry units, construction panels, dining tables, counter surfaces etc. NOVA CHEMICALS INC. (US) 2009-12-15 US claimed
EP-2001818-A2 LIGHTWEIGHT CONCRETE COMPOSITIONS CONTAINING ANTIMICROBIAL AGENTS Nova Chemicals Inc. (US) 2008-12-17 EP claimed
EP-1585751-A4 PEPTIDE DEFORMYLASE ACTIVATED PRODRUGS CELMED ONCOLOGY USA INC (CA) 2008-08-13 EP claimed
WO-2007111859-A2 LIGHTWEIGHT CONCRETE COMPOSITIONS CONTAINING ANTIMICROBIAL AGENTS NOVA CHEMICALS INC. (US) 2007-10-04 WO claimed
US-20070027224-A1 Lightweight concrete compositions containing antimicrobial agents SYNTHEON INC. 2007-02-01 US claimed
US-20040236096-A1 Peptide deformylase activated prodrugs NEWBIOTICS, INC. 2004-11-25 US claimed
WO-2004043400-A2 PEPTIDE DEFORMYLASE ACTIVATED PRODRUGS CELMED ONCOLOGY (USA), INC. (CA) 2004-05-27 WO claimed
EP-1263762-A4 ANTI-INFECTIVE ECTATM NEWBIOTICS INC (US) 2003-04-02 EP claimed
EP-1263762-A1 ANTI-INFECTIVE ECTATM Newbiotics Inc. (US) 2002-12-11 EP claimed
WO-2001064687-A1 ANTI-INFECTIVE ECTA?TM¿ NEWBIOTICS, INC. (US) 2001-09-07 WO claimed
US-6266951-B1 Cut resistant yarn and apparel WHIZARD PROTECTIVE WEAR CORP. 2001-07-31 US claimed
US-6260344-B1 CORE OF STAINLESS STEEL, GLASS FIBERS, OR POLYPHENYLENE TEREPHTHALAMIDE WRAPPED WITH MICROBIOCIDE TREATED ACRYLIC FIBER; PROTECTIVE CLOTHING, GLOVES WHIZARD PROTECTIVE WEAR CORP. 2001-07-17 US claimed
US-6045785-A COMPRISING A STEROL SULFATE, ALUMINUM CHLOROHYDRATE, AND AN ESTERASE INHIBITOR, A BACTERICIDAL AGENT, OR A BACTERIOSTATIC AGENT HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2000-04-04 US claimed
WO-1999035315-A1 CUT RESISTANT YARN AND APPAREL WHIZARD PROTECTIVE WEAR CORP. (US) 1999-07-15 WO claimed
WO-1996015107-A1 DITHIOCARBAMATE DERIVATIVES BAYER AKTIENGESELLSCHAFT (DE) 1996-05-23 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040236096-A1 Peptide deformylase activated prodrugs DNPEP, DPEP1, PEPD TTR 4046/4885HPGD 850/4885NR1I2 3302/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.