Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | F10 | P00742 | 1/20 | 0.42 |
| ▸ | PLG | P00747 | 1/20 | 0.42 |
| ▸ | PLAU | P00749 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | IGF1R | P08069 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL674008 | 0.87 | ALDH1A1 (0.52) | L3MBTL1ALDH1A1TDP1GLAMAPT | |
| SCHEMBL9825698 | 0.87 | ALDH1A1 (0.52) | L3MBTL1ALDH1A1TDP1GLAMAPT | |
| SCHEMBL27724474 | 0.83 | L3MBTL1 (0.49) | L3MBTL1ALDH1A1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL1053091 | 0.83 | ALDH1A1 (0.58) | L3MBTL1ALDH1A1TDP1GLAMAPT | |
| SCHEMBL8996035 | 0.82 | L3MBTL1 (0.51) | L3MBTL1CYP1A2CYP2D6CYP2C19TDP1 | |
| SCHEMBL29366998 | 0.81 | L3MBTL1 (0.58) | L3MBTL1ALDH1A1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL1242347 | 0.81 | L3MBTL1 (0.58) | L3MBTL1ALDH1A1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL28049884 | 0.81 | L3MBTL1 (0.58) | L3MBTL1ALDH1A1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL255562 | 0.80 | L3MBTL1 (0.81) | L3MBTL1ALDH1A1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL29635708 | 0.80 | L3MBTL1 (0.81) | L3MBTL1ALDH1A1CYP1A2CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009081259-A1 | PHENOXY-PYRIDYL DERIVATIVES | PFIZER INC. (US) | 2009-07-02 | — | — | WO | disclosed |