Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 15/20 | 0.71 |
| ▸ | S1PR3 | Q99500 | 12/20 | 0.71 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.71 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | ARG1 | P05089 | 1/20 | 0.33 |
| ▸ | ARG2 | P78540 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4015784 | 0.94 | S1PR1 (0.81) | S1PR1S1PR3S1PR5S1PR4 | |
| SCHEMBL4017370 | 0.89 | S1PR1 (0.62) | S1PR1S1PR3S1PR5HDAC1HDAC8 | |
| SCHEMBL4015886 | 0.88 | S1PR1 (0.72) | S1PR1S1PR3S1PR5S1PR4 | |
| SCHEMBL12743970 | 0.86 | S1PR1 (0.59) | S1PR1S1PR3S1PR5PPARGPPARA | |
| SCHEMBL385944 | 0.86 | S1PR1 (0.59) | S1PR1S1PR3S1PR5PPARGPPARA | |
| Hydrochloric Acid SCHEMBL1454101 | 0.85 | S1PR1 (0.58) | S1PR1S1PR3S1PR5PPARAHDAC1 | |
| SCHEMBL4016195 | 0.85 | S1PR1 (0.71) | S1PR1S1PR3S1PR5S1PR4PPARG | |
| SCHEMBL4019428 | 0.85 | S1PR1 (0.73) | S1PR1S1PR3S1PR5S1PR4 | |
| SCHEMBL4017372 | 0.83 | S1PR1 (0.71) | S1PR1S1PR3S1PR5S1PR4HDAC1 | |
| SCHEMBL385162 | 0.83 | S1PR1 (1.00) | S1PR1S1PR3S1PR5S1PR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1471054-B1 | AMINO ALCOHOL DERIVATIVE OR PHOSPHONIC ACID DERIVATIVE AND MEDICINAL COMPOSITION CONTAINING THESE | DAIICHI SANKYO CO LTD (JP) | 2009-07-01 | — | — | EP | claimed |