SCHEMBL4016170

SCHEMBL4016170

CCN(CC)C(=O)/C=C/C(=O)O

nearest known ligand 0.52

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.52
L3MBTL1 Q9Y468 1/20 0.52
ZDHHC20 Q5W0Z9 1/20 0.47
TSHR P16473 2/20 0.45
TP53 P04637 1/20 0.45
EGLN1 Q9GZT9 1/20 0.45
EGLN3 Q9H6Z9 1/20 0.45
HCAR2 Q8TDS4 5/20 0.43
ALDH1A1 P00352 1/20 0.40
MAPT P10636 1/20 0.38
PARP1 P09874 1/20 0.37
LMNA P02545 1/20 0.37
TRPM8 Q7Z2W7 1/20 0.37
LTB4R Q15722 1/20 0.36
LTB4R2 Q9NPC1 1/20 0.36
MMP1 P03956 1/20 0.36
MMP2 P08253 1/20 0.36
MMP3 P08254 1/20 0.36
MMP8 P22894 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1903390 1.00 NPC1 (0.52) NPC1L3MBTL1ZDHHC20TSHRTP53
SCHEMBL1395640 1.00 NPC1 (0.52) NPC1L3MBTL1ZDHHC20TSHRTP53
SCHEMBL1022195 0.89 NPC1 (0.54) NPC1L3MBTL1ZDHHC20TSHRTP53
SCHEMBL1395649 0.89 NPC1 (0.54) NPC1L3MBTL1ZDHHC20TSHRTP53
SCHEMBL1630772 0.89 NPC1 (0.54) NPC1L3MBTL1ZDHHC20TSHRTP53
SCHEMBL19917777 0.87 ZDHHC20 (0.50) NPC1L3MBTL1ZDHHC20TSHRTP53
SCHEMBL19854404 0.87 ZDHHC20 (0.50) NPC1L3MBTL1ZDHHC20TSHRTP53
SCHEMBL31265916 0.83 ZDHHC20 (0.41) NPC1L3MBTL1ZDHHC20TSHRTP53
SCHEMBL1832210 0.81 ZDHHC20 (0.53) ZDHHC20TSHRTP53EGLN1EGLN3
SCHEMBL1832212 0.81 ZDHHC20 (0.53) ZDHHC20TSHRTP53EGLN1EGLN3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119591659-A Tripterine acrylamide derivative and preparation method and application thereof 中国药科大学 2025-03-11 CN disclosed
WO-2024162401-A1 DUST-PROOFING MATERIAL, PROTECTIVE CLOTHING AND METHOD FOR PRODUCING DUST-PROOFING MATERIAL エム・エーライフマテリアルズ株式会社 2024-08-08 WO disclosed
EP-3512602-B1 INHIBITORS OF HEAT SHOCK FACTORS (HSF) AND USES THEREOF HSF PHARMACEUTICALS (CH) 2024-03-27 EP disclosed
US-11912831-B2 Hydroxyethylpyrrolidone ethacrylate/glycidyl ethacrylate copolymers ISP INVESTMENTS LLC (US) 2024-02-27 US disclosed
US-11515810-B2 Energy conversion film and energy conversion element using same YUPO CORPORATION (JP) 2022-11-29 US disclosed
WO-2022210605-A1 RECORDING PAPER 株式会社ユポ・コーポレーション 2022-10-06 WO disclosed
EP-3550620-B1 PIEZOELECTRIC ELEMENT AND MUSICAL INSTRUMENT YUPO CORP (JP) 2022-05-04 EP disclosed
CN-110214358-B Energy conversion film and energy conversion element using same 优泊公司 2022-03-22 CN disclosed
US-7482379-B2 Propenoyl hydrazides GEORGIA TECH RESEARCH CORPORATION (US) 2009-01-27 US disclosed
US-20050256058-A1 Propenoyl hydrazides NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2005-11-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11912831-B2 Hydroxyethylpyrrolidone ethacrylate/glycidyl ethacrylate copolymers MMAB, PCNA, HMBS NPC1 4879/4885L3MBTL1 1589/4885ZDHHC20 4590/4885
US-20050256058-A1 Propenoyl hydrazides DNPEP, HPN, PREP NPC1 2408/4885L3MBTL1 2501/4885ZDHHC20 819/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.