Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 6/20 | 0.45 |
| ▸ | DRD3 | P35462 | 6/20 | 0.45 |
| ▸ | DRD4 | P21917 | 5/20 | 0.45 |
| ▸ | HTR1A | P08908 | 2/20 | 0.45 |
| ▸ | HTR2A | P28223 | 2/20 | 0.45 |
| ▸ | HTR2C | P28335 | 2/20 | 0.45 |
| ▸ | HTR2B | P41595 | 2/20 | 0.45 |
| ▸ | PAK1 | Q13153 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.42 |
| ▸ | PREP | P48147 | 1/20 | 0.40 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.38 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4016348 | 0.94 | MEN1 (0.49) | DRD2DRD3DRD4HTR1AHTR2A | |
| SCHEMBL4022815 | 0.93 | DRD2 (0.50) | DRD2DRD3DRD4HTR1AHTR2A | |
| SCHEMBL4017305 | 0.89 | PAK1 (0.55) | DRD2DRD3DRD4HTR1AHTR2A | |
| SCHEMBL4021705 | 0.84 | PAK1 (0.50) | DRD2DRD3DRD4HTR1AHTR2A | |
| SCHEMBL4583323 | 0.82 | PAK1 (0.61) | DRD2DRD3DRD4HTR1AHTR2A | |
| SCHEMBL4023839 | 0.81 | MEN1 (0.52) | DRD2DRD3DRD4HTR1AHTR2A | |
| SCHEMBL4018523 | 0.81 | ALDH1A1 (0.59) | DRD2DRD3DRD4HTR1AHTR2A | |
| SCHEMBL4018498 | 0.81 | PAK1 (0.62) | DRD2DRD3DRD4HTR1AHTR2A | |
| SCHEMBL4019298 | 0.80 | PAK1 (0.54) | DRD2DRD3DRD4HTR1AHTR2A | |
| SCHEMBL4024845 | 0.80 | DRD2 (0.61) | DRD2DRD3DRD4HTR1AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2066654-A1 | N-(1-HETARYLPIPERIDIN-4-YL)(HET)ARYLAMIDES AS EP2 RECEPTOR MODULATORS | Bayer Schering Pharma AG (DE) | 2009-06-10 | — | — | EP | disclosed |
| WO-2008028691-A1 | N-(1-HETARYLPIPERIDIN-4-YL)(HET)ARYLAMIDES AS EP2 RECEPTOR MODULATORS | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2008-03-13 | — | — | WO | disclosed |