Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.40 |
| ▸ | TET3 | O43151 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | FOXO1 | Q12778 | 1/20 | 0.40 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.40 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.40 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.40 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4017819 | 0.92 | MEN1 (0.47) | MEN1KMT2AHDAC1HDAC4HDAC3 | |
| SCHEMBL4017820 | 0.91 | MAPT (0.50) | MEN1KMT2AMAPTNLRP3LMNA | |
| SCHEMBL4017823 | 0.91 | MAPT (0.50) | MEN1KMT2AMAPTNLRP3LMNA | |
| SCHEMBL4014345 | 0.91 | MMP1 (0.48) | MEN1KMT2AMMP1MMP2MMP9 | |
| SCHEMBL13982589 | 0.90 | MEN1 (0.43) | MEN1KMT2AHDAC1HDAC4HDAC3 | |
| SCHEMBL4017825 | 0.90 | MMP1 (0.50) | MEN1KMT2AHDAC4MAPTNLRP3 | |
| SCHEMBL4668502 | 0.89 | MEN1 (0.43) | MEN1KMT2AHDAC1HDAC4HDAC3 | |
| SCHEMBL4752215 | 0.89 | MEN1 (0.43) | MEN1KMT2AHDAC1HDAC4HDAC3 | |
| SCHEMBL4015839 | 0.89 | MEN1 (0.44) | MEN1KMT2AHDAC4MAPTNLRP3 | |
| SCHEMBL4668484 | 0.88 | MEN1 (0.44) | MEN1KMT2AHDAC1HDAC4HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2014287-A1 | Use of cinnamic acid derivatives as modulators of an EP2 receptor | Bayer Schering Pharma Aktiengesellschaft (DE) | 2009-01-14 | — | — | EP | claimed |
| EP-2014287-A1 | Use of cinnamic acid derivatives as modulators of an EP2 receptor | Bayer Schering Pharma Aktiengesellschaft (DE) | 2009-01-14 | — | — | EP | disclosed |