Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | TET3 | O43151 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | FOXO1 | Q12778 | 1/20 | 0.38 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.38 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.38 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4668502 | 1.00 | MEN1 (0.43) | MEN1KMT2ALMNAATMHDAC1 | |
| SCHEMBL4668484 | 0.91 | MEN1 (0.44) | MEN1KMT2ALMNAHDAC1MAPT | |
| SCHEMBL4017819 | 0.91 | MEN1 (0.47) | MEN1KMT2ALMNAHDAC1MAPT | |
| SCHEMBL4669514 | 0.90 | MEN1 (0.46) | MEN1KMT2ALMNAHDAC1MAPT | |
| SCHEMBL4754393 | 0.90 | MEN1 (0.46) | MEN1KMT2ALMNAHDAC1MAPT | |
| SCHEMBL4017823 | 0.90 | MAPT (0.50) | MEN1KMT2ALMNAMAPTNLRP3 | |
| SCHEMBL4017820 | 0.90 | MAPT (0.50) | MEN1KMT2ALMNAMAPTNLRP3 | |
| SCHEMBL4014345 | 0.90 | MMP1 (0.48) | MEN1KMT2AMMP1MMP2MMP9 | |
| SCHEMBL4016316 | 0.89 | MEN1 (0.43) | MEN1KMT2ALMNAHDAC1MAPT | |
| SCHEMBL13982589 | 0.89 | MEN1 (0.43) | MEN1KMT2ALMNAHDAC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008152097-A1 | CINNAMIC ACID DERIVATIVES AS MODULATORS OF THE EP2 RECEPTOR | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2008-12-18 | — | — | WO | claimed |
| WO-2008152097-A1 | CINNAMIC ACID DERIVATIVES AS MODULATORS OF THE EP2 RECEPTOR | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2008-12-18 | — | — | WO | disclosed |