Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | RXRA | P19793 | 4/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 4/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4015164 | 0.86 | ATM (0.52) | ATMKDM4EMEN1KMT2ANPC1 | |
| SCHEMBL4011715 | 0.82 | KCNH2 (0.42) | ATMKDM4EMEN1KMT2ANPC1 | |
| SCHEMBL4008876 | 0.82 | ATM (0.48) | ATMKDM4EMEN1KMT2ANPC1 | |
| SCHEMBL4016761 | 0.82 | ATM (0.55) | ATMKDM4EMEN1KMT2ANPC1 | |
| Hydrochloric Acid SCHEMBL4017566 | 0.78 | NPSR1 (0.49) | ATMKDM4EMEN1KMT2ANPC1 | |
| SCHEMBL4008882 | 0.77 | KCNH2 (0.39) | ATMKDM4EMEN1KMT2ANPC1 | |
| SCHEMBL8034096 | 0.76 | KDM4E (0.50) | ATMKDM4EMEN1KMT2ANPC1 | |
| SCHEMBL4014250 | 0.75 | MEN1 (0.44) | ATMKDM4EMEN1KMT2ANPC1 | |
| SCHEMBL4010260 | 0.75 | ATM (0.45) | ATMKDM4ERAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL4015161 | 0.73 | ATM (0.54) | ATMKDM4EMEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009080248-A1 | SUBSTITUTED 2-PHENYLPYRIMIDINE-5-CARBOXYLIC ACIDS AND THE USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-07-02 | — | — | WO | disclosed |