Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | DHPS | P49366 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | TYMP | P19971 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CTSA | P10619 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4015164 | 0.89 | ATM (0.52) | MEN1KMT2AATMHPGDTSHR | |
| SCHEMBL4008512 | 0.87 | MAPT (0.42) | MEN1KMT2AATMDHPSGAA | |
| SCHEMBL4008889 | 0.85 | DHPS (0.41) | ATMDHPSGAAHPGDNPSR1 | |
| SCHEMBL4007805 | 0.83 | CNR1 (0.41) | ATMTSHRNPSR1SMN1; SMN2ALDH1A1 | |
| SCHEMBL4007963 | 0.82 | CNR1 (0.42) | ATM | |
| SCHEMBL4014246 | 0.82 | MEN1 (0.46) | MEN1KMT2AATMDHPSGAA | |
| SCHEMBL4011472 | 0.81 | MAPT (0.39) | MEN1KMT2AATMHPGDTSHR | |
| SCHEMBL4016764 | 0.75 | ATM (0.53) | MEN1KMT2AATMGAAHPGD | |
| SCHEMBL8024769 | 0.75 | MAPT (0.45) | MEN1KMT2AGAAHPGDTSHR | |
| SCHEMBL4010260 | 0.75 | ATM (0.45) | ATMGAAHPGDTSHRNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009080248-A1 | SUBSTITUTED 2-PHENYLPYRIMIDINE-5-CARBOXYLIC ACIDS AND THE USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-07-02 | — | — | WO | disclosed |