Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.37 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.37 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.35 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.35 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4014170 | 0.87 | MAPT (0.43) | MAPTALDH1A1LMNATDP1RAB9A | |
| SCHEMBL4008643 | 0.86 | MAPT (0.46) | MAPTALDH1A1LMNATDP1RAB9A | |
| SCHEMBL4015164 | 0.85 | ATM (0.52) | ATMMAPTALDH1A1LMNATDP1 | |
| SCHEMBL4014101 | 0.84 | ALDH1A1 (0.41) | MAPTALDH1A1LMNATDP1RAB9A | |
| SCHEMBL4010115 | 0.84 | MAPT (0.39) | ATMMAPTALDH1A1LMNATDP1 | |
| SCHEMBL8030927 | 0.82 | ATM (0.46) | ATMMAPTALDH1A1LMNATDP1 | |
| SCHEMBL4008512 | 0.79 | MAPT (0.42) | ATMMAPTALDH1A1LMNATDP1 | |
| SCHEMBL4011731 | 0.78 | MAPT (0.41) | MAPTALDH1A1LMNATDP1RAB9A | |
| SCHEMBL4009770 | 0.76 | MAPT (0.37) | ATMMAPTALDH1A1LMNATDP1 | |
| SCHEMBL4015161 | 0.76 | ATM (0.54) | ATMALDH1A1TDP1RAB9APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009080248-A1 | SUBSTITUTED 2-PHENYLPYRIMIDINE-5-CARBOXYLIC ACIDS AND THE USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-07-02 | — | — | WO | disclosed |