SCHEMBL2232602

SCHEMBL2232602

CCCCCCC=CCCCCCCCCOCC(O)CO

nearest known ligand 0.88

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.80
DGKA P23743 1/20 0.60
HTT P42858 1/20 0.57
LPAR1 Q92633 2/20 0.54
LPAR3 Q9UBY5 2/20 0.54
FAAH O00519 2/20 0.54
P2RY10 O00398 1/20 0.53
ALDH1A1 P00352 1/20 0.51
CNR1 P21554 1/20 0.51
CNR2 P34972 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16086697 1.00 USP2 (0.80) USP2DGKAHTTLPAR1LPAR3
SCHEMBL15418245 1.00 USP2 (0.80) USP2DGKAHTTLPAR1LPAR3
SCHEMBL81179 1.00 USP2 (0.80) USP2DGKAHTTLPAR1LPAR3
SCHEMBL7065281 1.00 USP2 (0.80) USP2DGKAHTTLPAR1LPAR3
SCHEMBL7064549 1.00 USP2 (0.80) USP2DGKAHTTLPAR1LPAR3
SCHEMBL1962549 1.00 USP2 (0.80) USP2DGKAHTTLPAR1LPAR3
SCHEMBL81180 1.00 USP2 (0.80) USP2DGKAHTTLPAR1LPAR3
SCHEMBL2231761 1.00 USP2 (0.80) USP2DGKAHTTLPAR1LPAR3
SCHEMBL8577431 1.00 USP2 (0.80) USP2DGKAHTTLPAR1LPAR3
SCHEMBL8032180 1.00 USP2 (0.80) USP2DGKAHTTLPAR1LPAR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9206206-B2 Oxidized lipid compounds and uses thereof VASCULAR BIOGENICS LTD. (IL) 2015-12-08 US disclosed
EP-2826370-A2 Oxidized lipid compounds and uses thereof Vascular Biogenics Ltd. (IL) 2015-01-21 EP disclosed
EP-2826369-A2 Oxidized lipid compounds and uses thereof Vascular Biogenics Ltd. (IL) 2015-01-21 EP disclosed
EP-2348866-B1 OXIDIZED LIPID COMPOUNDS AND USES THEREOF VASCULAR BIOGENICS LTD (IL) 2015-01-07 EP disclosed
US-20130203707-A1 Oxidized Lipid Compounds and Uses Thereof VASCULAR BIOGENICS LTD. (IL) 2013-08-08 US disclosed
CN-102271517-A oxidized lipid compounds and uses thereof 2011-12-07 CN disclosed
US-20110207703-A1 OXIDIZED LIPID COMPOUNDS AND USES THEREOF VASCULAR BIOGENICS LTD. (IL) 2011-08-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130203707-A1 Oxidized Lipid Compounds and Uses Thereof LPO, GPX4, ALOX15B USP2 1186/4885DGKA 412/4885HTT 2468/4885
US-20110207703-A1 OXIDIZED LIPID COMPOUNDS AND USES THEREOF LPO, GPX4, ALOX15B USP2 1186/4885DGKA 412/4885HTT 2468/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.