Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 7/20 | 0.51 |
| ▸ | ERBB2 | P04626 | 7/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 3/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP3 | P08254 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | MMP12 | P39900 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
| ▸ | MMP14 | P50281 | 1/20 | 0.44 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.44 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28108051 | 0.86 | MLNR (0.53) | EGFRERBB2TSHRHSD17B10POLB | |
| SCHEMBL10580913 | 0.83 | TBXA2R (0.58) | EGFRERBB2TSHRHSD17B10CA2 | |
| SCHEMBL104746 | 0.82 | CA2 (0.62) | EGFRERBB2TSHRHSD17B10POLB | |
| SCHEMBL2922447 | 0.81 | POLB (0.49) | EGFRERBB2TSHRHSD17B10POLB | |
| SCHEMBL28293647 | 0.80 | TSHR (0.62) | TSHRHSD17B10CA2CA1CA9 | |
| SCHEMBL776229 | 0.80 | MAPT (0.61) | EGFRERBB2TSHRHSD17B10POLB | |
| Hydrochloric Acid SCHEMBL2170212 | 0.80 | CA2 (0.60) | EGFRERBB2TSHRHSD17B10POLB | |
| Fluoride SCHEMBL11185179 | 0.80 | CA2 (0.60) | EGFRERBB2TSHRHSD17B10POLB | |
| Methane SCHEMBL1421956 | 0.80 | CA2 (0.60) | EGFRERBB2TSHRHSD17B10POLB | |
| SCHEMBL1718452 | 0.80 | DRD3 (0.48) | TSHRHSD17B10POLBCA2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2074098-A2 | QUINOLINE COMPOUNDS | Wyeth (US) | 2009-07-01 | — | — | EP | disclosed |
| WO-2008049047-A2 | QUINOLINE COMPOUNDS | WYETH (US) | 2008-04-24 | — | — | WO | disclosed |