Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | IGF1R | P08069 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.37 |
| ▸ | AHR | P35869 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30456979 | 0.71 | AHR (0.62) | MEN1KMT2AIGF1RCYP3A4AHR | |
| SCHEMBL30513558 | 0.71 | CYP3A4 (0.46) | MEN1KMT2AIGF1RCYP3A4AHR | |
| SCHEMBL4594563 | 0.71 | ALDH1A1 (0.42) | MEN1KMT2AIGF1RCYP3A4AHR | |
| SCHEMBL15613033 | 0.71 | CYP3A4 (0.37) | MEN1KMT2AIGF1RCYP3A4AHR | |
| SCHEMBL8524080 | 0.71 | AHR (0.62) | MEN1KMT2AIGF1RCYP3A4AHR | |
| SCHEMBL8257515 | 0.71 | PKM (0.40) | MEN1KMT2AIGF1RCYP3A4AHR | |
| SCHEMBL3073324 | 0.71 | MEN1 (0.47) | MEN1KMT2AIGF1RCYP3A4AHR | |
| SCHEMBL1743402 | 0.71 | CYP3A4 (0.37) | MEN1KMT2AIGF1RCYP3A4AHR | |
| SCHEMBL4016972 | 0.71 | CYP3A4 (0.37) | MEN1KMT2ACYP3A4ALDH1A1MAPT | |
| SCHEMBL3464639 | 0.71 | MEN1 (0.47) | MEN1KMT2AIGF1RCYP3A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5024743-A | Prophylaxis and therapy of infectious diseases | MADAUS GMBH & CO. (DE) | 1991-06-18 | — | — | US | claimed |
| US-8540904-B2 | Composition for ultraviolet absorbent substance and ultraviolet absorbent substance comprising same | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2013-09-24 | — | — | US | disclosed |
| US-20120313058-A1 | COMPOSITION FOR ULTRAVIOLET ABSORBENT SUBSTANCE AND ULTRAVIOLET ABSORBENT SUBSTANCE COMPRISING SAME | SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) | 2012-12-13 | — | — | US | disclosed |