Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | WNT3A | P56704 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 7/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.47 |
| ▸ | GCK | P35557 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.46 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.45 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.45 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.45 |
| ▸ | KDM4A | O75164 | 3/20 | 0.45 |
| ▸ | KDM4B | O94953 | 3/20 | 0.45 |
| ▸ | KDM5B | Q9UGL1 | 3/20 | 0.45 |
| ▸ | KDM5C | P41229 | 1/20 | 0.45 |
| ▸ | MITF | O75030 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1619501 | 0.95 | RAB9A (0.53) | RAB9ALMNASMN1; SMN2NPC1L3MBTL1 | |
| SCHEMBL4011038 | 0.93 | LMNA (0.46) | RAB9ALMNASMN1; SMN2NPC1L3MBTL1 | |
| SCHEMBL1619362 | 0.92 | GCK (0.49) | LMNASMN1; SMN2WNT3AALDH1A1GCK | |
| SCHEMBL1621081 | 0.89 | GCK (0.57) | RAB9ALMNASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL1621098 | 0.85 | HTT (0.51) | RAB9ALMNASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL1621441 | 0.84 | GCK (0.58) | RAB9ALMNAALDH1A1GCKMAPT | |
| SCHEMBL1619354 | 0.84 | KMT2A (0.52) | RAB9ALMNASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL4011458 | 0.83 | GCK (0.51) | RAB9ALMNASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL10217207 | 0.82 | GCK (0.59) | RAB9ALMNASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL4162523 | 0.81 | GCK (0.50) | RAB9ALMNASMN1; SMN2NPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2074084-A1 | COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | Boehringer Ingelheim International GmbH (DE) | 2009-07-01 | — | — | EP | claimed |
| WO-2008039645-A1 | COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-04-03 | — | — | WO | claimed |