Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.38 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | CDK9 | P50750 | 1/20 | 0.38 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.38 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.38 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.37 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7016051 | 0.83 | LRRK2 (0.42) | MAPTALDH1A1L3MBTL1MEN1RECQL | |
| SCHEMBL7019238 | 0.80 | L3MBTL1 (0.40) | MAPTALDH1A1SMN1; SMN2CCNA2CDK2 | |
| SCHEMBL16612806 | 0.77 | EGFR (0.41) | PDPK1ADORA2AADORA1LRRK2MKNK1 | |
| SCHEMBL27393525 | 0.77 | DYRK1A (0.44) | CDK9PDPK1ADORA2AADORA1LRRK2 | |
| SCHEMBL14029857 | 0.77 | ADORA2A (0.43) | MAPTALDH1A1L3MBTL1ADORA2AADORA1 | |
| SCHEMBL16446295 | 0.76 | PDPK1 (0.39) | MAPTSMN1; SMN2PDPK1ADORA2AADORA1 | |
| SCHEMBL10012874 | 0.76 | ADORA2A (0.39) | MAPTALDH1A1SMN1; SMN2L3MBTL1ADORA2A | |
| SCHEMBL7655789 | 0.76 | DYRK1A (0.42) | MAPTALDH1A1L3MBTL1ADORA2AADORA1 | |
| SCHEMBL7958023 | 0.76 | HRH4 (0.45) | PDPK1ADORA2AADORA1MKNK1MKNK2 | |
| SCHEMBL2564796 | 0.76 | ADORA2A (0.42) | MAPTALDH1A1SMN1; SMN2L3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2014659-A1 | New hybrid compounds of nucleobases and organic redox molecules and their use | Universität Osnabrück (DE) | 2009-01-14 | — | — | EP | disclosed |
| WO-2008148560-A1 | NEW HYBRID COMPOUNDS OF NUCLEOBASES AND ORGANIC REDOX MOLECULES AND THEIR USE | Universität Osnabrück (DE) | 2008-12-11 | — | — | WO | disclosed |
| EP-0733633-B1 | Heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-05-28 | — | — | EP | disclosed |
| US-6211158-B1 | Desazapurine-nucleotide derivatives, processes for the preparation thereof, pharmaceutical compositions containing them and the use thereof for nucleic acid sequencing and as antiviral agents | ROCHE DIAGNOSTICS GMBH (DE) | 2001-04-03 | — | — | US | disclosed |
| EP-0733633-A1 | Heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-09-25 | — | — | EP | disclosed |
| EP-0286028-B1 | Derivatives of disazapurine nucleosides, process for their preparation and their use in the sequence analysis of nucleic acids and as antiviral agents | BOEHRINGER MANNHEIM GMBH (DE) | 1995-06-28 | — | — | EP | disclosed |