Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | TTBK1 | Q5TCY1 | 1/20 | 0.36 |
| ▸ | TTBK2 | Q6IQ55 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.34 |
| ▸ | CDK1 | P06493 | 1/20 | 0.34 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.34 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7016051 | 0.88 | LRRK2 (0.42) | L3MBTL1TTBK1TTBK2MAPTPDK1 | |
| SCHEMBL7015802 | 0.82 | NEK1 (0.39) | L3MBTL1ADORA2AADORA3HTTPDK1 | |
| SCHEMBL4016987 | 0.80 | MAPT (0.39) | L3MBTL1MAPK1ADORA2ALMNASMN1; SMN2 | |
| SCHEMBL14029857 | 0.72 | ADORA2A (0.43) | L3MBTL1ADORA2ALMNAMAPTPDK1 | |
| SCHEMBL7655789 | 0.70 | DYRK1A (0.42) | L3MBTL1ADORA2ALMNAMAPTPDK1 | |
| SCHEMBL161735 | 0.70 | ADORA2A (0.39) | L3MBTL1MAPK1ADORA2ALMNASMN1; SMN2 | |
| SCHEMBL2564796 | 0.70 | ADORA2A (0.42) | L3MBTL1ADORA2ALMNASMN1; SMN2HTT | |
| SCHEMBL10012874 | 0.70 | ADORA2A (0.39) | L3MBTL1ADORA2ALMNASMN1; SMN2HTT | |
| SCHEMBL7015801 | 0.69 | TTK (0.37) | ADORA2ASMN1; SMN2PDK1LRRK2ADORA1 | |
| SCHEMBL11835880 | 0.69 | CYP1A2 (0.51) | LMNASMN1; SMN2CDK2CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0733633-B1 | Heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-05-28 | — | — | EP | disclosed |
| EP-0733633-A1 | Heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-09-25 | — | — | EP | disclosed |