SCHEMBL4017031

SCHEMBL4017031

CC1=Nc2cccc(S(=O)(=O)Cl)c2C1(C)C

nearest known ligand 0.45

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45
ALDH1A1 P00352 1/20 0.31
HSD17B10 Q99714 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
TRPV4 Q9HBA0 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL101050 0.83 MEN1 (0.49) MEN1KMT2ATDP1
SCHEMBL4020207 0.83 MEN1 (0.54) MEN1KMT2A
SCHEMBL4014873 0.82 MEN1 (0.47) MEN1KMT2ATDP1
Potassium Ion SCHEMBL4014871 0.82 MEN1 (0.44) MEN1KMT2A
SCHEMBL4016429 0.81 MEN1 (0.43) MEN1KMT2A
SCHEMBL5699565 0.78 KMT2A (0.41) MEN1KMT2AALDH1A1HSD17B10
SCHEMBL5273065 0.73 MEN1 (0.51) MEN1KMT2AALDH1A1
SCHEMBL1049879 0.72 MEN1 (0.55) MEN1KMT2AALDH1A1
SCHEMBL31461336 0.72 MEN1 (0.55) MEN1KMT2AALDH1A1
SCHEMBL14566372 0.72 MEN1 (0.55) MEN1KMT2AALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1491591-B1 New fluorescence cyanine labels containing a sulfamido linker arm VISEN MEDICAL INC (US) 2009-07-01 EP disclosed
EP-1065250-B1 New fluorescent cyanine labels containing a sulfamido linker arm VISEN MEDICAL INC (US) 2004-12-08 EP disclosed
US-6448008-B1 IMMUNOLOGICAL BINDING REAGENT LABELLED WITH A FLUORESCENT COMPOUND AND METHOD OF ASSAYING AN ANALYTE IN A SAMPLE COMPRISING CONTACTING A NUCLEIC ACID PROBE OR AN IMMUNOLOGICALLY BINDING REAGENT LABELLED WITH A FLUORESCENT INNOSENSE, S.R.L. (IT) 2002-09-10 US disclosed
EP-1065250-A1 New fluorescent cyanine labels containing a sulfamido linker arm Innosense S.r.l. (IT) 2001-01-03 EP disclosed