SCHEMBL4014873

SCHEMBL4014873

CC1=Nc2cccc(S(=O)(=O)O)c2C1(C)C.[KH]

nearest known ligand 0.47

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
MYC P01106 1/20 0.36
TTR P02766 1/20 0.34
SNCA P37840 1/20 0.31
KDM4E B2RXH2 1/20 0.30
POLB P06746 1/20 0.30
APEX1 P27695 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
AURKA O14965 1/20 0.30
AURKB Q96GD4 1/20 0.30
ATIC P31939 1/20 0.30
SUMO2 P61956 1/20 0.30
SUMO1 P63165 1/20 0.30
SENP7 Q9BQF6 1/20 0.30
SENP2 Q9HC62 1/20 0.30
CYP1A2 P05177 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL101050 0.98 MEN1 (0.49) MEN1KMT2AMYCTTRSNCA
SCHEMBL14566372 0.83 MEN1 (0.55) MEN1KMT2AMYCTTRSNCA
SCHEMBL4017031 0.82 MEN1 (0.45) MEN1KMT2ATDP1
SCHEMBL12146309 0.82 MEN1 (0.54) MEN1KMT2AMYCTTRSNCA
Potassium Ion SCHEMBL4014871 0.81 MEN1 (0.44) MEN1KMT2A
SCHEMBL10064492 0.79 MEN1 (0.43) MEN1KMT2A
SCHEMBL4999732 0.79 MEN1 (0.35) MEN1KMT2AMYCAURKAAURKB
SCHEMBL5699565 0.77 KMT2A (0.41) MEN1KMT2AKDM4EAPEX1
SCHEMBL135180 0.76 MEN1 (0.36) MEN1KMT2A
SCHEMBL7701818 0.76 MEN1 (0.54) MEN1KMT2ATTRSNCATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1491591-B1 New fluorescence cyanine labels containing a sulfamido linker arm VISEN MEDICAL INC (US) 2009-07-01 EP disclosed
EP-1065250-B1 New fluorescent cyanine labels containing a sulfamido linker arm VISEN MEDICAL INC (US) 2004-12-08 EP disclosed
US-6448008-B1 IMMUNOLOGICAL BINDING REAGENT LABELLED WITH A FLUORESCENT COMPOUND AND METHOD OF ASSAYING AN ANALYTE IN A SAMPLE COMPRISING CONTACTING A NUCLEIC ACID PROBE OR AN IMMUNOLOGICALLY BINDING REAGENT LABELLED WITH A FLUORESCENT INNOSENSE, S.R.L. (IT) 2002-09-10 US disclosed
EP-1065250-A1 New fluorescent cyanine labels containing a sulfamido linker arm Innosense S.r.l. (IT) 2001-01-03 EP disclosed