Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 7/20 | 0.44 |
| ▸ | CNR1 | P21554 | 6/20 | 0.44 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.39 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4017105 | 0.91 | CNR2 (0.44) | CNR2CNR1GRM4ALDH1A1LMNA | |
| SCHEMBL1619416 | 0.88 | GRM4 (0.47) | CNR2CNR1GRM4ALDH1A1LMNA | |
| SCHEMBL4010398 | 0.87 | CNR2 (0.44) | CNR2CNR1GRM4MAPK13MAPK14 | |
| SCHEMBL4017166 | 0.82 | CNR2 (0.46) | CNR2CNR1GRM4MAPK13MAPK14 | |
| SCHEMBL4010397 | 0.79 | CNR2 (0.43) | CNR2CNR1GRM4ALDH1A1LMNA | |
| SCHEMBL1621011 | 0.78 | CNR2 (0.70) | CNR2CNR1MAPK14ALDH1A1GAA | |
| SCHEMBL1464868 | 0.73 | CNR2 (0.58) | CNR2CNR1ALDH1A1LMNAGAA | |
| SCHEMBL1463565 | 0.69 | CNR2 (0.46) | CNR2CNR1ALDH1A1LMNAGAA | |
| SCHEMBL1621385 | 0.69 | FFAR2 (0.53) | ALDH1A1LMNANPC1RAB9AMAPK1 | |
| SCHEMBL1619863 | 0.68 | KMT2A (0.44) | CNR2ALDH1A1LMNAGAANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2074084-A1 | COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | Boehringer Ingelheim International GmbH (DE) | 2009-07-01 | — | — | EP | disclosed |
| WO-2008039645-A1 | COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-04-03 | — | — | WO | disclosed |