Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 12/20 | 0.75 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.41 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | HTR1D | P28221 | 1/20 | 0.39 |
| ▸ | HTR1B | P28222 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | FLT1 | P17948 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4012753 | 0.92 | FAAH (0.75) | FAAHGRM4ABCB1PRKD1 | |
| SCHEMBL3933752 | 0.88 | FAAH (0.89) | FAAHMEN1NPC1RAB9AKMT2A | |
| SCHEMBL3936220 | 0.86 | FAAH (1.00) | FAAHMEN1NPC1RAB9AKMT2A | |
| SCHEMBL3935112 | 0.85 | FAAH (0.87) | FAAHABCB1MEN1NPC1RAB9A | |
| SCHEMBL3933423 | 0.85 | FAAH (0.87) | FAAHMEN1NPC1RAB9AKMT2A | |
| SCHEMBL3941489 | 0.84 | FAAH (0.83) | FAAHMEN1NPC1RAB9AKMT2A | |
| SCHEMBL3941505 | 0.84 | FAAH (0.80) | FAAHABCB1MEN1NPC1RAB9A | |
| SCHEMBL4014452 | 0.84 | FAAH (0.68) | FAAHGRM4NPC1RAB9A | |
| SCHEMBL3935343 | 0.84 | FAAH (0.89) | FAAHABCB1FLT1MEN1NPC1 | |
| SCHEMBL3935920 | 0.83 | FAAH (0.86) | FAAHMEN1NPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009011904-A1 | COMPOUNDS USEFUL AS FAAH MODULATORS AND USES THEREOF | RENOVIS, INC. (US) | 2009-01-22 | — | — | WO | disclosed |