SCHEMBL4017276

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4018526	0.86	KDR (0.67)	KDRFLT1NAMPTKMT2ASMN1; SMN2
	SCHEMBL4020953	0.81	KDR (0.53)	KDRFLT1NAMPTKMT2ASMN1; SMN2
	SCHEMBL4017975	0.81	KDR (0.58)	KDRFLT1NAMPTKMT2ASMN1; SMN2
	SCHEMBL4018288	0.80	KDR (0.71)	KDRFLT1NAMPTKMT2AMEN1
	SCHEMBL4019331	0.80	KDR (0.68)	KDRFLT1NAMPTKMT2ASMN1; SMN2
	SCHEMBL4023440	0.78	ESRRG (0.54)	KDRFLT1NAMPTKMT2ASMN1; SMN2
	SCHEMBL4017457	0.77	KDR (0.69)	KDRKMT2ASMN1; SMN2PKMMEN1
	SCHEMBL4018187	0.76	SMN1; SMN2 (0.52)	KDRFLT1NAMPTKMT2ASMN1; SMN2
	SCHEMBL4017439	0.74	PKM (0.46)	KDRKMT2ASMN1; SMN2PKMMEN1
	SCHEMBL4019378	0.74	KDR (0.65)	KDRKMT2ASMN1; SMN2MEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.