Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adipic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.92 |
| ▸ | TSHR | P16473 | 4/20 | 0.85 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.85 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.85 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.77 |
| ▸ | BLM | P54132 | 1/20 | 0.71 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.71 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.65 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.65 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.65 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.65 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.65 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.65 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.62 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.61 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.61 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.61 |
| ▸ | PPARG | P37231 | 5/20 | 0.61 |
| ▸ | PPARD | Q03181 | 5/20 | 0.61 |
| ▸ | PPARA | Q07869 | 5/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adipic Acid SCHEMBL1963560 | 1.00 | LMNA (0.92) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Adipic Acid SCHEMBL515200 | 1.00 | LMNA (0.92) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Sebacic Acid SCHEMBL7717227 | 0.96 | TSHR (0.92) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Azelaic Acid SCHEMBL4157618 | 0.96 | TSHR (0.92) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Hydrochloric Acid SCHEMBL688374 | 0.96 | TSHR (0.92) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Hydrochloric Acid SCHEMBL7717229 | 0.96 | TSHR (0.92) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Sebacic Acid SCHEMBL14809563 | 0.96 | TSHR (0.92) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Sebacic Acid SCHEMBL689154 | 0.96 | TSHR (0.92) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Sebacic Acid SCHEMBL14809040 | 0.96 | TSHR (0.92) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Hydrochloric Acid SCHEMBL8922192 | 0.96 | TSHR (0.92) | LMNATSHRNFKB1PMP22SLC22A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 369 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115385896-B | Preparation method of CSF-1R inhibitor intermediate or acid salt thereof | 上海和誉生物医药科技有限公司 | 2024-11-15 | — | — | CN | claimed |
| CN-115385897-B | Preparation method of CSF-1R inhibitor or acid salt thereof | 上海和誉生物医药科技有限公司 | 2024-11-08 | — | — | CN | claimed |
| CN-116848102-A | Crystalline CSF-1R inhibitor acid salt and preparation method and application thereof | 上海和誉生物医药科技有限公司 | 2023-10-03 | — | — | CN | claimed |
| CN-113318264-A | Degradable polyurethane biomaterial and preparation method and application thereof | 瑞聚再生(厦门)医学科技有限公司 | 2021-08-31 | — | — | CN | claimed |
| CN-109734900-B | Enzyme-degradable polypeptide-based polyester ammonia and preparation method and application thereof | 东华大学 | 2021-05-04 | — | — | CN | claimed |
| EP-2053034-B1 | Process for producing a chlorohydrin | SOLVAY (BE) | 2018-01-24 | — | — | EP | claimed |
| EP-1775278-B1 | Process for producing epoxy resins | SOLVAY (BE) | 2016-04-13 | — | — | EP | claimed |
| EP-1752435-B1 | Process for producing epichlorhydrin | SOLVAY (BE) | 2012-06-06 | — | — | EP | claimed |
| EP-1772446-B1 | Process for producing organic compounds from glycerol , the glycerol coming from renewable raw material | SOLVAY (BE) | 2010-10-20 | — | — | EP | claimed |
| EP-2053034-A1 | Process for producing a chlorohydrin | SOLVAY (Société Anonyme) (BE) | 2009-04-29 | — | — | EP | claimed |
| US-20070112224-A1 | Process for producing dichloropropanol from glycerol, the glycerol coming eventually from the conversion of animal fats in the manufacture of biodiesel | SOLVAY (SOCIETE ANONYME) (BE) | 2007-05-17 | — | — | US | claimed |
| EP-1775278-A1 | Process for producing epoxy resins | SOLVAY (Société Anonyme) (BE) | 2007-04-18 | — | — | EP | claimed |
| EP-1772446-A1 | Process for producing organic compounds from glycerol , the glycerol coming from renewable raw material | SOLVAY (Société Anonyme) (BE) | 2007-04-11 | — | — | EP | claimed |
| EP-1770081-A1 | Process for producing dichloropropanol from glycerol , the glycerol coming eventualy from the conversion of animal fats in the manufacture of biodiesel | SOLVAY (Société Anonyme) (BE) | 2007-04-04 | — | — | EP | claimed |
| EP-1760060-A1 | Process for producing dichloropropanol from glycerol | SOLVAY (Société Anonyme) (BE) | 2007-03-07 | — | — | EP | claimed |
| EP-1752436-A1 | Pseudo-azeotropic composition containing dichloropropanol and process for producing such composition | SOLVAY (Société Anonyme) (BE) | 2007-02-14 | — | — | EP | claimed |
| EP-1752435-A1 | Process for producing dichloropropanol from glycerol , the glycerol coming eventualy from the manufacture of biodiesel | SOLVAY (Société Anonyme) (BE) | 2007-02-14 | — | — | EP | claimed |
| US-3940390-A | Process for the production of 2,3,4,5,6,7-hexahydrocyclopenta-(3)-1,3-oxazine-2,4-dione compounds | BAYER AKTIENGESELLSCHAFT (DT) | 1976-02-24 | — | — | US | claimed |
| JP-4007559-A | — | — | None | — | — | JP | disclosed |
| US-3940390-A | Process for the production of 2,3,4,5,6,7-hexahydrocyclopenta-(3)-1,3-oxazine-2,4-dione compounds | BAYER AKTIENGESELLSCHAFT (DT) | 1976-02-24 | — | — | US | disclosed |