Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adipic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.92 |
| ▸ | TSHR | P16473 | 4/20 | 0.85 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.85 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.85 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.77 |
| ▸ | BLM | P54132 | 1/20 | 0.71 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.71 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.65 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.65 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.65 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.65 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.65 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.65 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.62 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.61 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.61 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.61 |
| ▸ | PPARG | P37231 | 5/20 | 0.61 |
| ▸ | PPARD | Q03181 | 5/20 | 0.61 |
| ▸ | PPARA | Q07869 | 5/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adipic Acid SCHEMBL1963560 | 1.00 | LMNA (0.92) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Adipic Acid SCHEMBL401737 | 1.00 | LMNA (0.92) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Sebacic Acid SCHEMBL7717227 | 0.96 | TSHR (0.92) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Azelaic Acid SCHEMBL4157618 | 0.96 | TSHR (0.92) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Hydrochloric Acid SCHEMBL688374 | 0.96 | TSHR (0.92) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Hydrochloric Acid SCHEMBL7717229 | 0.96 | TSHR (0.92) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Sebacic Acid SCHEMBL14809563 | 0.96 | TSHR (0.92) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Sebacic Acid SCHEMBL689154 | 0.96 | TSHR (0.92) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Sebacic Acid SCHEMBL14809040 | 0.96 | TSHR (0.92) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Hydrochloric Acid SCHEMBL8922192 | 0.96 | TSHR (0.92) | LMNATSHRNFKB1PMP22SLC22A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 582 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113262642-B | Ultrahigh-separation-selectivity nanofiltration membrane, and preparation method and application thereof | 中国科学院苏州纳米技术与纳米仿生研究所 | 2023-03-21 | — | — | CN | claimed |
| CN-115337800-A | High-desalination antioxidant polyamide reverse osmosis membrane, and preparation method and application thereof | 万华化学集团股份有限公司 | 2022-11-15 | — | — | CN | claimed |
| CN-114995061-B | Low-water-absorption positive photosensitive resin composition and preparation method and application thereof | 明士(北京)新材料开发有限公司 | 2022-11-01 | — | — | CN | claimed |
| CN-115220305-A | Positive photosensitive resin composition and preparation method and application thereof | 明士(北京)新材料开发有限公司 | 2022-10-21 | — | — | CN | claimed |
| CN-114995061-A | Low-water-absorption positive photosensitive resin composition and preparation method and application thereof | 明士(北京)新材料开发有限公司 | 2022-09-02 | — | — | CN | claimed |
| CN-112023727-B | Anti-pollution antibacterial reverse osmosis membrane, preparation method and application thereof | 万华化学集团股份有限公司 | 2022-07-12 | — | — | CN | claimed |
| CN-112280530-B | Sealant for lining sliding sleeve sealing system and preparation method thereof | 海隆石油产品技术服务（上海）有限公司 | 2022-04-05 | — | — | CN | claimed |
| CN-111229053-B | High-flux nanofiltration membrane, and preparation method and application thereof | 中国科学院苏州纳米技术与纳米仿生研究所 | 2022-03-08 | — | — | CN | claimed |
| CN-110982044-B | MDI-based isocyanate-terminated prepolymers and polyurethane foams prepared therefrom | 万华化学集团股份有限公司 | 2021-12-14 | — | — | CN | claimed |
| CN-113262642-A | Ultrahigh-separation-selectivity nanofiltration membrane, and preparation method and application thereof | 中国科学院苏州纳米技术与纳米仿生研究所 | 2021-08-17 | — | — | CN | claimed |
| US-6075139-A | ADDING DROPWISE A WATER IMMISCIBLE ORGANIC SOLVENT CONTAINING A BIFUNCTIONAL ACIDIC REACTANT TO AQUEOUS SOLUTION OF SUCROSE, AND MAINTAINING REACTION UNTIL SUCROSE ESTER OLIGOMER OR POLYMER IS PRODUCED AT INTERFACE | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2000-06-13 | — | — | US | claimed |
| WO-1998003528-A1 | LINEAR AND CYCLIC SUCROSE REACTION PRODUCTS, THEIR PREPARATION AND THEIR USE | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 1998-01-29 | — | — | WO | claimed |
| EP-0431124-B1 | NEW PLASTICS BASED ON FATTY ACIDS | FRISCHE GMBH (DE) | 1996-05-22 | — | — | EP | claimed |
| EP-0438579-B1 | NEW MONOMERIC UNITS OBTAINED FROM HYDROXY FATTY ACIDS, FOR MANUFACTURING PLASTICS | FRISCHE GMBH (DE) | 1995-10-25 | — | — | EP | claimed |
| US-5312889-A | Hydroxyfatty-acid-based monomers for producing plastics | BATTELLE-INSTITUT E.V. (DE) | 1994-05-17 | — | — | US | claimed |
| US-5279766-A | Reacted with polyol and(or) diamine | ICI AMERICAS INC. (US) | 1994-01-18 | — | — | US | claimed |
| EP-0441527-A2 | Stabilized polymer latex composition | ICI AMERICAS INC. (US) | 1991-08-14 | — | — | EP | claimed |
| US-5011883-A | Containing protective colloid and alkyd resin | ICI AMERICAS INC. (US) | 1991-04-30 | — | — | US | claimed |
| US-4100116-A | AMINATION | BAYER AKTIENGESELLSCHAFT (DE) | 1978-07-11 | — | — | US | claimed |
| US-3940390-A | Process for the production of 2,3,4,5,6,7-hexahydrocyclopenta-(3)-1,3-oxazine-2,4-dione compounds | BAYER AKTIENGESELLSCHAFT (DT) | 1976-02-24 | — | — | US | claimed |