Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CLK1 | P49759 | 1/20 | 0.43 |
| ▸ | IDE | P14735 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | CCR5 | P51681 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4017495 | 0.88 | ALDH1A1 (0.54) | MEN1KMT2AALDH1A1CLK1IDE | |
| SCHEMBL14183873 | 0.87 | ALDH1A1 (0.54) | MEN1KMT2AALDH1A1CLK1IDE | |
| SCHEMBL4024837 | 0.80 | ALDH1A1 (0.56) | MEN1KMT2AALDH1A1CLK1IDE | |
| SCHEMBL14183875 | 0.80 | ALDH1A1 (0.56) | MEN1KMT2AALDH1A1CLK1IDE | |
| SCHEMBL4017674 | 0.80 | MEN1 (0.45) | MEN1KMT2AALDH1A1CLK1IDE | |
| SCHEMBL4018523 | 0.76 | ALDH1A1 (0.59) | MEN1KMT2AALDH1A1CLK1IDE | |
| SCHEMBL4918308 | 0.76 | DRD2 (0.49) | MEN1KMT2ADRD2DRD3 | |
| SCHEMBL4018447 | 0.76 | MEN1 (0.63) | MEN1KMT2AALDH1A1CLK1IDE | |
| SCHEMBL4018926 | 0.76 | PAK1 (0.55) | MEN1KMT2A | |
| SCHEMBL4025066 | 0.76 | ALDH1A1 (0.51) | MEN1KMT2AALDH1A1CLK1IDE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2066654-A1 | N-(1-HETARYLPIPERIDIN-4-YL)(HET)ARYLAMIDES AS EP2 RECEPTOR MODULATORS | Bayer Schering Pharma AG (DE) | 2009-06-10 | — | — | EP | claimed |
| WO-2008028691-A1 | N-(1-HETARYLPIPERIDIN-4-YL)(HET)ARYLAMIDES AS EP2 RECEPTOR MODULATORS | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2008-03-13 | — | — | WO | claimed |