Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR4 | P51679 | 1/20 | 0.57 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.55 |
| ▸ | PDE5A | O76074 | 2/20 | 0.54 |
| ▸ | ACP1 | P24666 | 2/20 | 0.54 |
| ▸ | OGG1 | O15527 | 1/20 | 0.54 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.53 |
| ▸ | GBA1 | P04062 | 5/20 | 0.50 |
| ▸ | LCK | P06239 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TOP2A | P11388 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4911813 | 0.76 | ADORA2A (0.60) | CCR4TLR7PDE5AACP1OGG1 | |
| SCHEMBL4908801 | 0.76 | KCNN2 (0.59) | CCR4TLR7PDE5AACP1OGG1 | |
| SCHEMBL4912379 | 0.76 | KCNN2 (0.59) | CCR4TLR7PDE5AACP1OGG1 | |
| SCHEMBL4913903 | 0.76 | KCNN2 (0.59) | CCR4TLR7PDE5AACP1OGG1 | |
| SCHEMBL4911365 | 0.74 | KCNN2 (0.57) | CCR4TLR7PDE5AACP1OGG1 | |
| SCHEMBL4176633 | 0.74 | KCNN2 (0.60) | PDE10AMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL4907646 | 0.74 | CCR4 (0.54) | CCR4TLR7PDE5AACP1OGG1 | |
| SCHEMBL30896243 | 0.74 | CCR4 (0.73) | CCR4TLR7PDE5AACP1OGG1 | |
| SCHEMBL11743074 | 0.74 | CCR4 (0.73) | CCR4TLR7PDE5AACP1OGG1 | |
| SCHEMBL4013746 | 0.74 | MKNK1 (0.53) | PDE10ALCKALDH1A1KDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017133664-A1 | BICYCLIC PYRIDINE AND PYRIMIDINE DERIVATIVES AND THEIR USE IN THE TREATMENT， AMELIORATION OR PREVENTION OF INFLUENZA | SAVIRA PHARMACEUTICALS GMBH (AT) | 2017-08-10 | — | — | WO | claimed |
| US-8222262-B2 | Indazolyl derivatives useful as potassium channel modulating agents | NEUROSEARCH A/S (DK) | 2012-07-17 | — | — | US | claimed |
| US-20090325989-A1 | INDAZOLYL DERIVATIVES USEFUL AS POTASSIUM CHANNEL MODULATING AGENTS | NEUROSEARCH A/S (DK) | 2009-12-31 | — | — | US | claimed |
| EP-2074113-A1 | INDAZOLYL DERIVATIVES USEFUL AS POTASSIUM CHANNEL MODULATING AGENTS | NeuroSearch A/S (DK) | 2009-07-01 | — | — | EP | claimed |
| WO-2008040753-A1 | INDAZOLYL DERIVATIVES USEFUL AS POTASSIUM CHANNEL MODULATING AGENTS | NEUROSEARCH A/S (DK) | 2008-04-10 | — | — | WO | claimed |
| US-8222262-B2 | Indazolyl derivatives useful as potassium channel modulating agents | NEUROSEARCH A/S (DK) | 2012-07-17 | — | — | US | disclosed |
| US-20090325989-A1 | INDAZOLYL DERIVATIVES USEFUL AS POTASSIUM CHANNEL MODULATING AGENTS | NEUROSEARCH A/S (DK) | 2009-12-31 | — | — | US | disclosed |
| EP-2074113-A1 | INDAZOLYL DERIVATIVES USEFUL AS POTASSIUM CHANNEL MODULATING AGENTS | NeuroSearch A/S (DK) | 2009-07-01 | — | — | EP | disclosed |
| WO-2008040753-A1 | INDAZOLYL DERIVATIVES USEFUL AS POTASSIUM CHANNEL MODULATING AGENTS | NEUROSEARCH A/S (DK) | 2008-04-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090325989-A1 | INDAZOLYL DERIVATIVES USEFUL AS POTASSIUM CHANNEL MODULATING AGENTS | KCND2, KCNN3, KCNJ2 | CCR4 4403/4885TLR7 3233/4885PDE5A 1518/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.