Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.40 |
| ▸ | CCR5 | P51681 | 1/20 | 0.40 |
| ▸ | IDE | P14735 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4017652 | 0.88 | CYP1A2 (0.43) | CCNE1CDK2 | |
| SCHEMBL4024538 | 0.81 | CLK1 (0.52) | ALDH1A1MAPK1PDGFRBIDEMEN1 | |
| SCHEMBL4018805 | 0.79 | CCNE1 (0.56) | ALDH1A1MAPK1PDGFRBIDEMEN1 | |
| SCHEMBL4017882 | 0.79 | CLK1 (0.48) | ALDH1A1MAPK1PDGFRBIDEMEN1 | |
| SCHEMBL4014341 | 0.78 | ALDH1A1 (0.59) | ALDH1A1MAPK1CCR5IDEMEN1 | |
| SCHEMBL4015431 | 0.76 | ALDH1A1 (0.55) | ALDH1A1MAPK1CCR5IDEMEN1 | |
| SCHEMBL14214179 | 0.76 | ALDH1A1 (0.55) | ALDH1A1MAPK1CCR5IDEMEN1 | |
| SCHEMBL4016423 | 0.75 | ALDH1A1 (0.55) | ALDH1A1MAPK1CCR5IDEMEN1 | |
| SCHEMBL4018937 | 0.74 | ALDH1A1 (0.52) | ALDH1A1MAPK1CCR5IDEMEN1 | |
| SCHEMBL14252974 | 0.73 | CLK1 (0.51) | ALDH1A1MAPK1PDGFRBCCR5IDE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2066654-A1 | N-(1-HETARYLPIPERIDIN-4-YL)(HET)ARYLAMIDES AS EP2 RECEPTOR MODULATORS | Bayer Schering Pharma AG (DE) | 2009-06-10 | — | — | EP | disclosed |
| WO-2008028691-A1 | N-(1-HETARYLPIPERIDIN-4-YL)(HET)ARYLAMIDES AS EP2 RECEPTOR MODULATORS | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2008-03-13 | — | — | WO | disclosed |