SCHEMBL4017978

SCHEMBL4017978

CC(C)(C)OC(=O)C1CC(O)CN1

nearest known ligand 0.41

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 4/20 0.41
DPP8 Q6V1X1 4/20 0.41
DPP9 Q86TI2 4/20 0.41
CHRM2 P08172 1/20 0.39
CHRM1 P11229 1/20 0.39
CHRM3 P20309 1/20 0.39
SMYD3 Q9H7B4 1/20 0.33
MAPK1 P28482 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.32
CYP1A2 P05177 1/20 0.31
CYP2D6 P10635 1/20 0.31
ALOX15 P16050 1/20 0.31
CYP2C19 P33261 1/20 0.31
SLC1A3 P43003 1/20 0.31
SLC1A2 P43004 1/20 0.31
SLC1A1 P43005 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL695946 1.00 DPP4 (0.41) DPP4DPP8DPP9CHRM2CHRM1
SCHEMBL29308170 1.00 DPP4 (0.41) DPP4DPP8DPP9CHRM2CHRM1
SCHEMBL21673908 1.00 DPP4 (0.41) DPP4DPP8DPP9CHRM2CHRM1
SCHEMBL28146362 1.00 DPP4 (0.41) DPP4DPP8DPP9CHRM2CHRM1
Hydrochloric Acid SCHEMBL30914110 0.98 DPP4 (0.40) DPP4DPP8DPP9CHRM2CHRM1
SCHEMBL4463526 0.86 DPP4 (0.37) DPP4DPP8DPP9CHRM2CHRM1
SCHEMBL3997238 0.86 DPP4 (0.37) DPP4DPP8DPP9CHRM2CHRM1
SCHEMBL9949501 0.84 CHRM2 (0.41) DPP4DPP8DPP9CHRM2CHRM1
SCHEMBL9949495 0.84 CHRM2 (0.41) DPP4DPP8DPP9CHRM2CHRM1
SCHEMBL4559703 0.82 DPP4 (0.38) DPP4DPP8DPP9CHRM2CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120202206-A Cyclic benzimidazole derivatives as cGAS inhibitors 勃林格殷格翰国际有限公司 2025-06-24 CN disclosed
CN-118574827-A BRM targeting compounds and related methods of use 阿维纳斯运营公司 2024-08-30 CN disclosed
CN-101821234-B Phenoxypyrrolidine derivatives, their use and compositions THESAN PHARMACEUTICALS INC 2014-06-25 CN disclosed
CN-102026985-A Quinazoline derivatives as RAF kinase modulators and methods and uses thereof AMBIT BIOSCIENCES CORPORATON 2011-04-20 CN disclosed
CN-101821234-A Phenoxypyrrolidine derivatives, their use and compositions PFIZER 2010-09-01 CN disclosed
EP-2074099-A1 QUINOLINONE DERIVATIVES Tibotec Pharmaceuticals Ltd. (IE) 2009-07-01 EP disclosed
CN-101400668-A 2-(cyclic amino)-pyrimidone derivatives as TPK1 inhibitors MITSUBISHI PHARMA CORP (JP) 2009-04-01 CN disclosed
CN-101312968-A Indazoles, benzothiazoles, benzoisothiazoles, benzisoxazoles, pyrazolopyridines, isothiazolopyridines, and preparation and uses thereof MEMORY PHARM CORP (US) 2008-11-26 CN disclosed
WO-2008037784-A1 QUINOLINONE DERIVATIVES TIBOTEC PHARMACEUTICALS LTD. (IE) 2008-04-03 WO disclosed
CN-101142227-A Novel betulin derivatives, preparation thereof and use thereof PANACOS PHARMACEUTICALS INC (US) 2008-03-12 CN disclosed