SCHEMBL4018037

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4017143	0.89	KDR (0.70)	KDRNAMPTFLT1MAPTPKM
	SCHEMBL4021262	0.87	KDR (0.64)	KDRNAMPTMAPTALDH1A1GAA
	SCHEMBL4022500	0.86	KDR (0.60)	KDRNAMPTFLT1P2RX1MAPT
	SCHEMBL4021513	0.86	KDR (0.63)	KDRALDH1A1GAAHPGDALOX15
	SCHEMBL4023063	0.86	KDR (0.68)	KDRMAPTALDH1A1HPGDHTT
	SCHEMBL4019855	0.86	KDR (0.63)	KDRMAPTALDH1A1HPGDPKM
	SCHEMBL4017094	0.86	KDR (0.66)	KDRFLT1P2RX1MAPTALDH1A1
	SCHEMBL4019387	0.85	KDR (0.61)	KDRALDH1A1PKML3MBTL1KMT2A
	SCHEMBL4018049	0.84	KDR (0.66)	KDRFLT1MAPTPKML3MBTL1
	SCHEMBL4023108	0.84	KDR (0.61)	KDRFLT1MAPTALDH1A1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.