SCHEMBL4019855

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4021262	0.91	KDR (0.64)	KDRKMT2APKML3MBTL1MEN1
	SCHEMBL4021513	0.90	KDR (0.63)	KDRKMT2APKML3MBTL1SMN1; SMN2
	SCHEMBL4017944	0.90	KDR (0.72)	KDRKMT2APKML3MBTL1MEN1
	SCHEMBL4023063	0.88	KDR (0.68)	KDRKMT2APKML3MBTL1MEN1
	SCHEMBL4018762	0.87	KDR (0.64)	KDRKMT2APKML3MBTL1BRAF
	SCHEMBL4019387	0.86	KDR (0.61)	KDRKMT2APKML3MBTL1MEN1
	SCHEMBL4018037	0.86	KDR (0.61)	KDRKMT2APKML3MBTL1MAPT
	SCHEMBL4019331	0.85	KDR (0.68)	KDRKMT2APKML3MBTL1MEN1
	SCHEMBL4017456	0.85	KDR (0.67)	KDRKMT2APKML3MBTL1MEN1
	SCHEMBL4016924	0.85	KDR (0.67)	KDRKMT2APKML3MBTL1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.