Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MTOR | P42345 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.38 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.38 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.37 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1308905 | 0.75 | MAPT (0.61) | MAPTL3MBTL1MTORALDH1A1MEN1 | |
| SCHEMBL4455822 | 0.74 | PIK3CA (0.56) | MTORPIK3CBPIK3CAPIK3R1PIK3CG | |
| SCHEMBL4020573 | 0.73 | MAPT (0.45) | MAPTL3MBTL1MTORALDH1A1MEN1 | |
| SCHEMBL8251599 | 0.72 | AR (0.58) | MTORALDH1A1KMT2AHTTMAPK1 | |
| SCHEMBL38827 | 0.72 | MAPT (0.57) | MAPTL3MBTL1MTORALDH1A1MEN1 | |
| SCHEMBL28998051 | 0.70 | ALDH1A1 (0.59) | MAPTL3MBTL1MTORALDH1A1MEN1 | |
| SCHEMBL28998047 | 0.69 | ALDH1A1 (0.62) | MAPTL3MBTL1ALDH1A1MEN1KMT2A | |
| SCHEMBL3596552 | 0.68 | MAPT (0.49) | MAPTMTORALDH1A1MEN1KMT2A | |
| SCHEMBL28932426 | 0.67 | MAPT (0.44) | MAPTL3MBTL1MTORALDH1A1MEN1 | |
| SCHEMBL1310780 | 0.67 | MAPT (0.60) | MAPTL3MBTL1ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009093981-A1 | TRIAZINE COMPOUNDS AS KINASE INHIBITORS | S BIO PTE LTD (SG) | 2009-07-30 | — | — | WO | disclosed |
| WO-2009093981-A1 | TRIAZINE COMPOUNDS AS KINASE INHIBITORS | S BIO PTE LTD (SG) | 2009-07-30 | — | — | WO | disclosed |