Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | PIK3CA | P42336 | 6/20 | 0.45 |
| ▸ | MTOR | P42345 | 6/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.39 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | JAK3 | P52333 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4018233 | 0.81 | PIK3CA (0.65) | MAPTL3MBTL1PIK3CAMTORHTT | |
| SCHEMBL4018669 | 0.78 | PIK3CA (0.58) | MAPTL3MBTL1PIK3CAMTORHTT | |
| SCHEMBL1308905 | 0.76 | MAPT (0.61) | MAPTL3MBTL1PIK3CAMTORHTT | |
| SCHEMBL4018366 | 0.73 | MAPT (0.44) | MAPTL3MBTL1PIK3CAMTORHTT | |
| SCHEMBL38827 | 0.73 | MAPT (0.57) | MAPTL3MBTL1PIK3CAMTORHTT | |
| SCHEMBL28998051 | 0.71 | ALDH1A1 (0.59) | MAPTL3MBTL1PIK3CAMTORHTT | |
| SCHEMBL28998047 | 0.70 | ALDH1A1 (0.62) | MAPTL3MBTL1HTTLMNAALDH1A1 | |
| SCHEMBL6626404 | 0.68 | PIK3CB (0.87) | MAPTL3MBTL1PIK3CAMTORPIK3CB | |
| SCHEMBL28932426 | 0.68 | MAPT (0.44) | MAPTL3MBTL1PIK3CAMTORHTT | |
| SCHEMBL777891 | 0.67 | HRH1 (0.55) | MAPTL3MBTL1PIK3CAHTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009093981-A1 | TRIAZINE COMPOUNDS AS KINASE INHIBITORS | S BIO PTE LTD (SG) | 2009-07-30 | — | — | WO | disclosed |
| WO-2009093981-A1 | TRIAZINE COMPOUNDS AS KINASE INHIBITORS | S BIO PTE LTD (SG) | 2009-07-30 | — | — | WO | disclosed |