Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | PAK1 | Q13153 | 8/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.41 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.40 |
| ▸ | SUV39H1 | O43463 | 1/20 | 0.40 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.40 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.38 |
| ▸ | MAP3K5 | Q99683 | 2/20 | 0.37 |
| ▸ | MAP3K6 | O95382 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 3/20 | 0.37 |
| ▸ | CNR2 | P34972 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4020867 | 0.90 | CYP1A2 (0.55) | CYP1A2CYP2D6PAK1MCHR1CRHR1 | |
| SCHEMBL4016229 | 0.88 | ALDH1A1 (0.49) | — | |
| SCHEMBL4018965 | 0.79 | CYP1A2 (0.54) | CYP1A2CYP2D6PAK1SUV39H1PRMT1 | |
| SCHEMBL4018931 | 0.77 | ALDH1A1 (0.60) | MCHR1 | |
| SCHEMBL4024856 | 0.77 | PAK1 (0.67) | CYP1A2CYP2D6PAK1SUV39H1PRMT1 | |
| SCHEMBL14183882 | 0.77 | ALDH1A1 (0.57) | — | |
| SCHEMBL4022769 | 0.76 | CYP1A2 (0.55) | CYP1A2CYP2D6PAK1SUV39H1PRMT1 | |
| SCHEMBL4584564 | 0.76 | MCHR1 (0.51) | CYP1A2PAK1MCHR1CRHR1 | |
| SCHEMBL4019280 | 0.75 | CYP1A2 (0.54) | CYP1A2CYP2D6PAK1SUV39H1PRMT1 | |
| SCHEMBL4024034 | 0.75 | PAK1 (0.55) | CYP1A2CYP2D6PAK1SUV39H1PRMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2066654-A1 | N-(1-HETARYLPIPERIDIN-4-YL)(HET)ARYLAMIDES AS EP2 RECEPTOR MODULATORS | Bayer Schering Pharma AG (DE) | 2009-06-10 | — | — | EP | disclosed |
| WO-2008028691-A1 | N-(1-HETARYLPIPERIDIN-4-YL)(HET)ARYLAMIDES AS EP2 RECEPTOR MODULATORS | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2008-03-13 | — | — | WO | disclosed |