SCHEMBL4018614

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1940433	0.88	L3MBTL1 (0.52)	L3MBTL1CYP1A2CYP3A4ALPGCYP2C9
	SCHEMBL4024240	0.86	L3MBTL1 (0.54)	L3MBTL1CYP1A2CYP3A4ALPGCYP2C9
	SCHEMBL1941188	0.86	L3MBTL1 (0.51)	L3MBTL1CYP1A2CYP3A4ALPGCYP2C9
	SCHEMBL1939690	0.83	L3MBTL1 (0.49)	L3MBTL1CYP1A2CYP3A4ALPGCYP2C9
	SCHEMBL4019876	0.80	PTPRG (0.67)	L3MBTL1CYP1A2CYP3A4ALPGCYP2C9
	SCHEMBL1784766	0.79	L3MBTL1 (0.45)	L3MBTL1CYP1A2CYP3A4ALPGCYP2C9
	SCHEMBL1496405	0.78	KDR (0.47)	L3MBTL1CYP1A2CYP3A4ALPGCYP2C9
	SCHEMBL4017874	0.78	KDR (0.52)	L3MBTL1CYP1A2CYP3A4ALPGCYP2C9
	SCHEMBL1940258	0.77	L3MBTL1 (0.50)	L3MBTL1CYP1A2CYP3A4ALPGCYP2C9
	SCHEMBL4017975	0.77	KDR (0.58)	L3MBTL1CYP1A2CYP3A4ALPGCYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.