SCHEMBL4019876

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4021401	0.81	PTPRC (0.75)	PTPRGPTPRCMAPTKMT2APTPN1
	SCHEMBL4018614	0.80	L3MBTL1 (0.52)	PTPRGPTPRCMAPTPTPN1NPSR1
	SCHEMBL7509205	0.80	PTPRG (1.00)	PTPRGPTPRCMAPTKMT2APTPN1
	SCHEMBL7830138	0.78	PTPRG (1.00)	PTPRGPTPRCMAPTKMT2APTPN1
	SCHEMBL1943028	0.77	PTPRC (0.48)	PTPRGPTPRCMAPTKMT2ANPSR1
	SCHEMBL1800354	0.72	PTPRC (0.53)	PTPRGPTPRCMAPTKMT2APTPN1
	SCHEMBL7825081	0.72	L3MBTL1 (0.69)	PTPRGPTPRCMAPTKMT2AEPHX1
	SCHEMBL7823399	0.71	PTPRC (0.75)	PTPRGPTPRCMAPTKMT2APTPN1
	SCHEMBL6550957	0.71	KMT2A (1.00)	PTPRGPTPRCMAPTKMT2AEPHX1
	SCHEMBL1496386	0.71	PTPRC (0.59)	PTPRGPTPRCMAPTKMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.