Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAK1 | Q13153 | 1/20 | 0.42 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.39 |
| ▸ | PRKDC | P78527 | 6/20 | 0.39 |
| ▸ | WDR5 | P61964 | 2/20 | 0.38 |
| ▸ | CNR1 | P21554 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4017243 | 0.91 | PAK1 (0.49) | PAK1MAP3K5HTR1ADRD2DRD4 | |
| SCHEMBL4018349 | 0.88 | PAK1 (0.51) | PAK1MAP3K5HTR1ADRD2DRD4 | |
| SCHEMBL4024014 | 0.86 | PAK1 (0.52) | PAK1MAP3K5PRKDCCNR1KCNH2 | |
| SCHEMBL4023212 | 0.82 | PAK1 (0.52) | PAK1MAP3K5HTR1ADRD2DRD4 | |
| SCHEMBL4021294 | 0.79 | PAK1 (0.61) | PAK1P2RX7PRKDC | |
| SCHEMBL4582560 | 0.79 | PAK1 (0.52) | PAK1MAP3K5HTR1ADRD2DRD4 | |
| SCHEMBL4018523 | 0.79 | ALDH1A1 (0.59) | PAK1HTR1ADRD2DRD4HTR2A | |
| SCHEMBL4019702 | 0.79 | P2RX7 (0.54) | PAK1MAP3K5HTR1ADRD2DRD4 | |
| SCHEMBL4016900 | 0.78 | PAK1 (0.54) | PAK1MAP3K5HTR1ADRD2DRD4 | |
| SCHEMBL4024415 | 0.77 | PAK1 (0.52) | PAK1MAP3K5HTR1ADRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2066654-A1 | N-(1-HETARYLPIPERIDIN-4-YL)(HET)ARYLAMIDES AS EP2 RECEPTOR MODULATORS | Bayer Schering Pharma AG (DE) | 2009-06-10 | — | — | EP | claimed |
| WO-2008028691-A1 | N-(1-HETARYLPIPERIDIN-4-YL)(HET)ARYLAMIDES AS EP2 RECEPTOR MODULATORS | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2008-03-13 | — | — | WO | claimed |