Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 5/20 | 0.58 |
| ▸ | MTOR | P42345 | 5/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TACR2 | P21452 | 1/20 | 0.38 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.37 |
| ▸ | SORD | Q00796 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4018233 | 0.83 | PIK3CA (0.65) | PIK3CAMTORMAPTL3MBTL1MAPK1 | |
| SCHEMBL8012484 | 0.80 | PIK3CA (0.74) | PIK3CAMTORPIK3CBPIK3R1 | |
| SCHEMBL4020573 | 0.78 | MAPT (0.45) | PIK3CAMTORMAPTL3MBTL1MAPK1 | |
| SCHEMBL1308905 | 0.75 | MAPT (0.61) | PIK3CAMTORMAPTL3MBTL1MAPK1 | |
| SCHEMBL8003263 | 0.75 | PIK3CA (0.75) | PIK3CAMTORPIK3CBPIK3R1 | |
| SCHEMBL28606435 | 0.75 | MAPT (0.56) | PIK3CAMAPTL3MBTL1MAPK1SMN1; SMN2 | |
| SCHEMBL8008189 | 0.74 | PIK3CA (1.00) | PIK3CAMTORPIK3CBPIK3R1 | |
| SCHEMBL15386251 | 0.73 | MAPT (0.50) | MAPTL3MBTL1MAPK1SMN1; SMN2HTT | |
| SCHEMBL1310780 | 0.73 | MAPT (0.60) | PIK3CAMAPTL3MBTL1MAPK1SMN1; SMN2 | |
| SCHEMBL38827 | 0.72 | MAPT (0.57) | PIK3CAMTORMAPTL3MBTL1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009093981-A1 | TRIAZINE COMPOUNDS AS KINASE INHIBITORS | S BIO PTE LTD (SG) | 2009-07-30 | — | — | WO | disclosed |
| WO-2009093981-A1 | TRIAZINE COMPOUNDS AS KINASE INHIBITORS | S BIO PTE LTD (SG) | 2009-07-30 | — | — | WO | disclosed |