Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18832171 | 1.00 | CHRM2 (0.40) | CHRM2CHRM4CHRM5CHRM3ALDH1A1 | |
| SCHEMBL18832209 | 1.00 | CHRM2 (0.40) | CHRM2CHRM4CHRM5CHRM3ALDH1A1 | |
| SCHEMBL4022679 | 0.89 | CHRM2 (0.38) | CHRM2CHRM4CHRM5CHRM3ALDH1A1 | |
| SCHEMBL4017183 | 0.87 | ALDH1A1 (0.40) | CHRM2CHRM4CHRM5CHRM3ALDH1A1 | |
| SCHEMBL4020352 | 0.86 | ALDH1A1 (0.41) | CHRM2CHRM4CHRM5CHRM3ALDH1A1 | |
| SCHEMBL4013801 | 0.86 | ALDH1A1 (0.41) | CHRM2CHRM4CHRM5CHRM3ALDH1A1 | |
| SCHEMBL4016137 | 0.86 | ALDH1A1 (0.41) | CHRM2CHRM4CHRM5CHRM3ALDH1A1 | |
| SCHEMBL4022074 | 0.86 | ALDH1A1 (0.41) | CHRM2CHRM4CHRM5CHRM3ALDH1A1 | |
| SCHEMBL4015796 | 0.86 | ALDH1A1 (0.41) | CHRM2CHRM4CHRM5CHRM3ALDH1A1 | |
| SCHEMBL4016149 | 0.86 | ALDH1A1 (0.41) | CHRM2CHRM4CHRM5CHRM3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111467346-B | Pyridone derivatives with tetrahydropyranylmethyl groups | 第一三共株式会社 | 2023-05-16 | — | — | CN | disclosed |
| US-20220002277-A1 | PYRIDONE DERIVATIVE HAVING TETRAHYDROPYRANYLMETHYL GROUP | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2022-01-06 | — | — | US | disclosed |
| US-11208403-B2 | Pyridone derivatives having tetrahydropyranylmethyl groups | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2021-12-28 | — | — | US | disclosed |
| EP-3168219-B1 | PYRIDONE DERIVATIVE HAVING TETRAHYDROPYRANYL METHYL GROUP | DAIICHI SANKYO CO LTD (JP) | 2021-03-31 | — | — | EP | disclosed |
| CN-106604920-B | Pyridone derivatives with tetrahydropyranylmethyl groups | 第一三共株式会社 | 2020-06-09 | — | — | CN | disclosed |
| US-10442797-B2 | Pyridone derivatives having tetrahydropyranylmethyl groups | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2019-10-15 | — | — | US | disclosed |
| US-20180148436-A2 | PYRIDONE DERIVATIVES HAVING TETRAHYDROPYRANYLMETHYL GROUPS | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2018-05-31 | — | — | US | disclosed |
| US-20170183329-A1 | PYRIDONE DERIVATIVE HAVING TETRAHYDROPYRANYLMETHYL GROUP | DAIICHI SANKYO CO LTD (JP) | 2017-06-29 | — | — | US | disclosed |
| EP-3168219-A1 | PYRIDONE DERIVATIVE HAVING TETRAHYDROPYRANYL METHYL GROUP | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2017-05-17 | — | — | EP | disclosed |
| EP-1085540-B1 | SOLID ELECTROLYTIC CAPACITOR AND METHOD FOR PREPARING THE SAME | SHOWA DENKO KK (JP) | 2009-07-01 | — | — | EP | disclosed |
| US-6466421-B1 | Solid electrolytic capacitor and method for producing the same | SHOWA DENKO K.K. (JP) | 2002-10-15 | — | — | US | disclosed |
| US-6344966-B1 | ELECTRICALLY CONDUCTING POLYMER LAYER CONTAINS AS A DOPANT AN ANION OF(1) ALKOXY-SUBSTITUTED NAPHTHALENESULFONATE, (2) A HETEROCYCLIC SULFONATE, OR (3) AN ANION OF AN ALIPHATIC POLYCYCLIC COMPOUND | SHOWA DENKO K.K. (JP) | 2002-02-05 | — | — | US | disclosed |
| EP-1085540-A1 | SOLID ELECTROLYTIC CAPACITOR AND METHOD FOR PREPARING THE SAME | Showa Denko K K (JP) | 2001-03-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220002277-A1 | PYRIDONE DERIVATIVE HAVING TETRAHYDROPYRANYLMETHYL GROUP | AXL, TYRO3, LCK | CHRM2 133/4885CHRM4 342/4885CHRM5 335/4885 |
| US-10442797-B2 | Pyridone derivatives having tetrahydropyranylmethyl groups | AXL, TYRO3, PDXK | CHRM2 100/4885CHRM4 347/4885CHRM5 357/4885 |
| US-20170183329-A1 | PYRIDONE DERIVATIVE HAVING TETRAHYDROPYRANYLMETHYL GROUP | AXL, TYRO3, PDXK | CHRM2 134/4885CHRM4 419/4885CHRM5 440/4885 |
| US-11208403-B2 | Pyridone derivatives having tetrahydropyranylmethyl groups | AXL, TYRO3, PDXK | CHRM2 100/4885CHRM4 347/4885CHRM5 357/4885 |
| US-20180148436-A2 | PYRIDONE DERIVATIVES HAVING TETRAHYDROPYRANYLMETHYL GROUPS | AXL, TYRO3, PDXK | CHRM2 100/4885CHRM4 347/4885CHRM5 357/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.