Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | SLC2A4 | P14672 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29444840 | 0.86 | MEN1 (0.56) | ALDH1A1CYP3A4CYP2D6KDM4EGLA | |
| SCHEMBL4716095 | 0.83 | ALDH1A1 (0.54) | ALDH1A1CYP3A4CYP2D6KDM4EGLA | |
| Gapicomine SCHEMBL1037773 | 0.81 | SLC2A4 (0.61) | ALDH1A1CYP3A4CYP2D6CYP2C19SLC2A4 | |
| SCHEMBL1659835 | 0.80 | ALDH1A1 (0.71) | ALDH1A1CYP3A4CYP2D6KDM4EGLA | |
| Gapicomine SCHEMBL9336954 | 0.79 | SLC2A4 (0.59) | ALDH1A1CYP3A4CYP2D6SLC2A4MEN1 | |
| SCHEMBL10054983 | 0.79 | SLC2A4 (0.59) | ALDH1A1CYP2D6KDM4EGLASLC2A4 | |
| Gapicomine SCHEMBL6121683 | 0.79 | SLC2A4 (0.59) | ALDH1A1CYP3A4CYP2D6SLC2A4MEN1 | |
| SCHEMBL3976803 | 0.78 | ALDH1A1 (0.54) | ALDH1A1CYP3A4CYP2D6KDM4EGLA | |
| SCHEMBL6831037 | 0.78 | ALDH1A1 (0.54) | ALDH1A1CYP3A4CYP2D6KDM4EGLA | |
| SCHEMBL3741348 | 0.78 | ALDH1A1 (0.50) | ALDH1A1CYP3A4CYP2D6KDM4EGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7524823-B2 | Macrolides | BASILEA PHARMACEUTICA AG (CH) | 2009-04-28 | — | — | US | disclosed |
| EP-1846430-B1 | NEW MACROLIDES | BASILEA PHARMACEUTICA AG (CH) | 2009-04-01 | — | — | EP | disclosed |
| EP-1846430-A1 | NEW MACROLIDES | Basilea Pharmaceutica AG (CH) | 2007-10-24 | — | — | EP | disclosed |
| US-20060264387-A1 | Macrolides | BASILEA PHARMACEUTICA AG (CH) | 2006-11-23 | — | — | US | disclosed |
| WO-2006084410-A1 | NEW MACROLIDES | BASILEA PHARMACEUTICA AG (CH) | 2006-08-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060264387-A1 | Macrolides | PPME1, MGAM, SMPD1 | ALDH1A1 3507/4885CYP3A4 689/4885CYP2D6 460/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.