Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.72 |
| ▸ | LMNA | P02545 | 4/20 | 0.72 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.72 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.50 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.50 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.50 |
| ▸ | MMP1 | P03956 | 1/20 | 0.50 |
| ▸ | MMP2 | P08253 | 1/20 | 0.50 |
| ▸ | MMP9 | P14780 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4018980 | 1.00 | ALDH1A1 (0.72) | ALDH1A1LMNACYP2C19CYP2D6KMT2A | |
| SCHEMBL26761468 | 0.91 | ALDH1A1 (0.85) | ALDH1A1LMNACYP2C19CYP2D6KMT2A | |
| SCHEMBL5175917 | 0.84 | ALDH1A1 (1.00) | ALDH1A1LMNACYP2C19CYP2D6KMT2A | |
| SCHEMBL4021293 | 0.84 | ALDH1A1 (1.00) | ALDH1A1LMNACYP2C19CYP2D6KMT2A | |
| SCHEMBL4021288 | 0.84 | ALDH1A1 (1.00) | ALDH1A1LMNACYP2C19CYP2D6KMT2A | |
| SCHEMBL5331523 | 0.83 | LMNA (1.00) | ALDH1A1LMNACYP2C19CYP2D6KMT2A | |
| SCHEMBL5331527 | 0.83 | LMNA (1.00) | ALDH1A1LMNACYP2C19CYP2D6KMT2A | |
| SCHEMBL11927837 | 0.83 | ALDH1A1 (0.72) | ALDH1A1LMNACYP2C19CYP2D6KMT2A | |
| SCHEMBL3633280 | 0.83 | ALDH1A1 (0.72) | ALDH1A1LMNACYP2C19CYP2D6KMT2A | |
| SCHEMBL15431334 | 0.83 | ALDH1A1 (0.72) | ALDH1A1LMNACYP2C19CYP2D6KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7482379-B2 | Propenoyl hydrazides | GEORGIA TECH RESEARCH CORPORATION (US) | 2009-01-27 | — | — | US | disclosed |
| EP-1723124-A1 | PROPENOYL HYDRAZIDES | Georgia Tech Research Corporation (US) | 2006-11-22 | — | — | EP | disclosed |
| US-20050256058-A1 | Propenoyl hydrazides | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2005-11-17 | — | — | US | disclosed |
| WO-2005080353-A1 | PROPENOYL HYDRAZIDES | GEORGIA TECH RESEARCH CORPORATION (US) | 2005-09-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050256058-A1 | Propenoyl hydrazides | DNPEP, HPN, PREP | ALDH1A1 2687/4885LMNA 2599/4885CYP2C19 4677/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.