Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.66 |
| ▸ | HPGD | P15428 | 1/20 | 0.66 |
| ▸ | IP6K1 | Q92551 | 11/20 | 0.60 |
| ▸ | IP6K2 | Q9UHH9 | 8/20 | 0.60 |
| ▸ | IP6K3 | Q96PC2 | 7/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.60 |
| ▸ | TP53 | P04637 | 2/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.60 |
| ▸ | NPC1 | O15118 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3846806 | 0.83 | MEN1 (0.67) | MEN1KMT2AALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL1757999 | 0.83 | ALDH1A1 (0.61) | MEN1KMT2AALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL10982180 | 0.81 | MAPT (0.61) | MEN1KMT2AALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL8589245 | 0.80 | MEN1 (1.00) | MEN1KMT2AALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL26565408 | 0.79 | KMT2A (0.73) | MEN1KMT2AALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL10396461 | 0.79 | ALDH1A1 (0.66) | MEN1KMT2AALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL10933962 | 0.79 | ALDH1A1 (1.00) | MEN1KMT2AALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL10396405 | 0.79 | ALDH1A1 (0.60) | MEN1KMT2AALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL9926035 | 0.78 | IP6K1 (0.64) | MEN1KMT2AALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL10839597 | 0.78 | IP6K1 (0.64) | MEN1KMT2AALDH1A1SMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1740640-B1 | DIBENZODIAZOCINE POLYMERS | SOLVAY SPECIALTY POLYMERS USA L L C (US) | 2012-06-13 | — | — | EP | disclosed |
| US-20110059948-A1 | QUINOLINE, NAPHTHALENE AND CONFORMATIONALLY CONSTRAINED QUINOLINE OR NAPHTHALENE DERIVATIVES AS ANTI-MYCOBACTERIAL AGENTS | THE INSTITUTE OF MOLECULAR MEDICINE (IN) | 2011-03-10 | — | — | US | disclosed |
| US-20110059948-A1 | QUINOLINE, NAPHTHALENE AND CONFORMATIONALLY CONSTRAINED QUINOLINE OR NAPHTHALENE DERIVATIVES AS ANTI-MYCOBACTERIAL AGENTS | THE INSTITUTE OF MOLECULAR MEDICINE (IN) | 2011-03-10 | — | — | US | disclosed |
| US-20110059948-A1 | QUINOLINE, NAPHTHALENE AND CONFORMATIONALLY CONSTRAINED QUINOLINE OR NAPHTHALENE DERIVATIVES AS ANTI-MYCOBACTERIAL AGENTS | THE INSTITUTE OF MOLECULAR MEDICINE (IN) | 2011-03-10 | — | — | US | disclosed |
| WO-2009091324-A1 | QUINOLINE, NAPHTHALENE AND CONFORMATIONALLY CONSTRAINED QUINOLINE OR NAPHTHALENE DERIVATES AS ANTI-MYCOBACTERIAL AGENTS | CHATTOPADHYAYA JYOTI (SE) | 2009-07-23 | — | — | WO | disclosed |
| US-7238771-B2 | Dibenzodiazocine polymers | SOLVAY ADVANCED POLYMERS, L.L.C. (US) | 2007-07-03 | — | — | US | disclosed |
| US-7238771-B2 | Dibenzodiazocine polymers | SOLVAY ADVANCED POLYMERS, L.L.C. (US) | 2007-07-03 | — | — | US | disclosed |
| US-7196094-B2 | Farnesyl transferase inhibiting 6-heterocyclylmethyl quinoline and quinazoline derivatives | JANSSEN PHARMACEUTICA, N.V. (BE) | 2007-03-27 | — | — | US | disclosed |
| US-4579679-A | Electroactive polymers | CHEVRON RESEARCH COMPANY (US) | 1986-04-01 | — | — | US | disclosed |
| EP-0126064-A4 | ELECTROACTIVE POLYMERS. | CHEVRON RES (US) | 1985-07-01 | — | — | EP | disclosed |
| US-4519937-A | DOPED UNITS OF A FUSED NITROGEN-CONTAINING UNSATURATED HETEROCYCLIC RING | CHEVRON RESEARCH COMPANY (US) | 1985-05-28 | — | — | US | disclosed |
| US-4519938-A | TRACTABLE, DOPED HETEROCYCLIC RINGS | CHEVRON RESEARCH COMPANY (US) | 1985-05-28 | — | — | US | disclosed |
| EP-0126064-A1 | ELECTROACTIVE POLYMERS | CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) | 1984-11-28 | — | — | EP | disclosed |
| WO-1984002030-A1 | ELECTROACTIVE POLYMERS | CHEVRON RES (US) | 1984-05-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110059948-A1 | QUINOLINE, NAPHTHALENE AND CONFORMATIONALLY CONSTRAINED QUINOLINE OR NAPHTHALENE DERIVATIVES AS ANTI-MYCOBACTERIAL AGENTS | NQO1, NQO2, NDUFV1 | MEN1 1176/4885KMT2A 3953/4885ALDH1A1 1830/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.