NDUFV1 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
Auraptene (SCHEMBL2535029)	1.00	5/20
Auraptene (SCHEMBL2535034)	1.00	5/20
SCHEMBL8491443	0.56	4/20
SCHEMBL8489900	0.52	4/20
SCHEMBL8489907	0.52	4/20
SCHEMBL8492838	0.52	4/20
SCHEMBL8492845	0.52	4/20
SCHEMBL8489902	0.51	4/20
SCHEMBL8489908	0.51	4/20
SCHEMBL8491154	0.51	4/20
SCHEMBL8491160	0.51	4/20
SCHEMBL8491619	0.50	4/20
SCHEMBL8491624	0.50	4/20
SCHEMBL8491634	0.50	4/20
SCHEMBL8494171	0.50	4/20
SCHEMBL8494175	0.50	4/20
SCHEMBL8494177	0.50	4/20
7-Prenyloxycoumarin (SCHEMBL4898255)	0.79	3/20
SCHEMBL712741	0.57	3/20
Geiparvarin (SCHEMBL2532495)	0.56	3/20

Clinical trials — most relevant to NDUFV1 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Phase III Trial of Coenzyme Q10 in Mitochondrial Disease	PHASE3	COMPLETED
A Study of the Efficacy and Safety of MT1621 in Thymidine Kinase 2 (TK2) Deficiency (Treatment naïve)	PHASE3	WITHDRAWN
Effect of Montelukast Versus Co Enzyme in Sepsis	PHASE2/PHASE3	COMPLETED
Mitochondrial Dysfunction in the Pathophysiology and Treatment of Bipolar Disorder	PHASE2	WITHDRAWN
Efficacy of KL1333 in Adult Patients With Primary Mitochondrial Disease	PHASE2	RECRUITING
A Study of Bezafibrate in Mitochondrial Myopathy	PHASE2	COMPLETED
A Study to Evaluate Vitamin B3 Derivative to Treat Mitochondrial Myopathy	PHASE2	ACTIVE_NOT_RECRUITING
Trial of Nicotinamide Riboside and Co-enzyme Q10 in Chronic Kidney Disease	PHASE2	COMPLETED
Does Clinical Treatment of Mitochondrial Dysfunction Impact Autism Spectrum Disorder (ASD)?	PHASE1	UNKNOWN
Genomic Profiling of Mitochondrial Disease - Imaging Analysis for Precise Mitochondrial Medicine	nan	COMPLETED
The Natural History of Mitochondrial Diseases	nan	RECRUITING
Evaluation of Impact of Disease and Visual Disability on Quality of Life and Loss of Independence of Patients Living in France With Leber's Hereditary Optic Neuropathy (LHON) Through Qualitative and Quantitative Data Collection	nan	COMPLETED
Tissue Sample Study for Mitochondrial Disorders	nan	ENROLLING_BY_INVITATION
North American Mitochondrial Disease Consortium Patient Registry and Biorepository (NAMDC)	nan	RECRUITING
MITOMICS : a Multi-OMICS Approach for the Diagnosis of Mitochondrial Diseases	nan	RECRUITING
GDF-15 as a Biomarker for Mitochondrial Disease	nan	COMPLETED
Identification of Large-Scale Mutations of POLG Gene by QMPSF in Patients With Mitochondrial DNA Instability.	nan	UNKNOWN
Identification of New Candidate Genes in Patients With Mitochondrial Disease by High Resolution Chromosome Analysis on DNA Chip	nan	COMPLETED
Natural History in Primary Mitochondrial Myopathies	nan	RECRUITING
Nicotinamide Riboside and Mitochondrial Biogenesis	nan	COMPLETED
Effect of Subtle Energy Transmission and Tao Calligraphy Mindfulness Practice on Mitochondrial DNA in Peripheral Blood Leukocytes	nan	NOT_YET_RECRUITING
Mitoquines in COPD	nan	UNKNOWN
EPI-743 for Mitochondrial Respiratory Chain Diseases	nan	NO_LONGER_AVAILABLE
A Study Into the Underlying Biochemical Pathways Involved in Parkinson's Disease, Such as Mitochondrial (Cellular Powerhouse) Dysfunction	nan	COMPLETED
Universal Rare Gene Study: A Registry and Natural History Study of Retinal Dystrophies Associated With Rare Disease-Causing Genetic Variants	nan	RECRUITING
The Genetics of Diabetes in Southern California Chinese Americans	nan	WITHDRAWN
Survey on Supplement Use in Mitochondrial Disease	nan	COMPLETED
Diagnostic Odyssey Survey 2	nan	COMPLETED
Calf Muscle Strength in Mitochondrial Diseases	nan	COMPLETED
Cardiac Mitochondrial Function in Explanted Human Hearts	nan	UNKNOWN

Related proteins — ESM-2 sequence neighbours (a NDUFV1 binder may also engage these)

Protein	Name	Similarity
Q0MQI6	—	1.000	Q0MQI6 →
Q91YT0	—	1.000	Q91YT0 →
Q0MQI5	—	1.000	Q0MQI5 →
P25708	—	1.000	P25708 →
Q0MQI4	—	1.000	Q0MQI4 →
P24917	—	1.000	P24917 →
Q9FNN5	—	1.000	Q9FNN5 →
Q8HXQ9	—	0.999	Q8HXQ9 →
Q92406	—	0.999	Q92406 →
Q54I90	—	0.995	Q54I90 →
Q56222	—	0.990	Q56222 →
P29913	—	0.990	P29913 →
P56912	—	0.990	P56912 →
P9WIV7	—	0.989	P9WIV7 →
O07948	—	0.989	O07948 →
P65568	—	0.988	P65568 →
P33901	—	0.988	P33901 →
P31979	—	0.988	P31979 →
Q9I0J7	—	0.986	Q9I0J7 →
P22317	—	0.986	P22317 →
P9WIV6	—	0.986	P9WIV6 →
Q92JB2	—	0.986	Q92JB2 →
Q9XAQ9	—	0.985	Q9XAQ9 →
P56913	—	0.985	P56913 →
Q9ZE33	—	0.985	Q9ZE33 →
A0A0F7TWW9	—	0.985	A0A0F7TWW9 →
Q68XY3	—	0.985	Q68XY3 →
A8GM77	—	0.984	A8GM77 →
C1F1E7	—	0.984	C1F1E7 →
Q89AU2	—	0.984	Q89AU2 →